Usefulness of follicular fluid estradiol and progesterone concentration measurement in predicting outcome of IVF/ICSI natural cyclesGavrić-Lovrec, Vida (Avtor) Vlaisavljević, Veljko (Avtor) Kovačič, Borut (Avtor) Gorenjak, Maksimiljan (Avtor) Reljič, Milan (Avtor) folikularna tekočinanaravni ciklusestradiolprogesteronIVF/ICSI izhodPurpose: The aim of the study was to establish whether follicular fluid (FF) estradiol (E2) and progesterone (P) measurement could be used to predict the outcome of unstimulated IVF/ICSI cycles. Methods: 91 women underwent 150 unstimulated IVF/ICSI cycles (78 IVF and 72 ICSI). Follicular fluid samples were collected at the time of oocyte recovery. Using the ttest, FF E2 and FF P levels and their ratios (FF P/FF E2) were compared between cycles with successful (with oocyte) and unsuccessful (without oocyte) oocyte recovery, between cycles with and without fertilization and between nonconception and conception cycles. Results: The oocyte recovery rate was 86.7% (123/150), the fertilization rate 68.3% (84/123) and the pregnancy rate per oocyte recovery 14.0% (21/150). The average FF E2 level was 3530 +/- 1339 nmol/L, average FF P 20649 +/- 9489 nmol/Land average FF P/FF E2 ratio 7.18 +/- 6.42. There were no statistically significant differences in FF E2, FF P levels and their ratio between cycles with unsuccessful and successful oocyte recovery, between cycles without and with fertilization, and between nonconception and conception cycles. Conclusion: From the FF E2 and P levels and their ratio, it is not possible to make inferences to the likelihood of oocyte recovery, fertilization and conception in unstimulated IVF/ICSI cycles.20122015-07-10 12:23:25Znanstveno delo49634UDK: 618.177-089.888.11OceCobissID: 242526720COBISS_ID: 4331327ISSN pri članku: 1855-5640NUK URN: URN:SI:UM:DK:ZG2TNZIUsl