Clostridium difficile ribotypes in humans and animals in BrazilSilveira Silva, Rodrigo Otávio (Avtor) Rupnik, Maja (Avtor) Diniz, Amanda Nádia (Avtor) Vilela, Eduardo Garcia (Avtor) Faria Lobato, Francisco Carlos (Avtor) Clostridium difficilepseudomembranous colitiszoonosisClostridium difficile is an emerging enteropathogen responsible for pseudomembranous colitis in humans and diarrhoea in several domestic and wild animal species. Despite its known importance, there are few studies aboutC. difficile polymerase chain reaction (PCR) ribotypes in Brazil and the actual knowledge is restricted to studies on human isolates. The aim of the study was therefore to compare C. difficileribotypes isolated from humans and animals in Brazil. Seventy-six C. difficile strains isolated from humans (n = 25), dogs (n = 23), piglets (n = 12), foals (n = 7), calves (n = 7), one cat, and one manned wolf were distributed into 24 different PCR ribotypes. Among toxigenic strains, PCR ribotypes 014/020 and 106 were the most common, accounting for 14 (18.4%) and eight (10.5%) samples, respectively. Fourteen different PCR ribotypes were detected among human isolates, nine of them have also been identified in at least one animal species. PCR ribotype 027 was not detected, whereas 078 were found only in foals. This data suggests a high diversity of PCR ribotypes in humans and animals in Brazil and support the discussion of C. difficile as a zoonotic pathogen.20152016-05-11 04:01:24Znanstveno delo59309ISSN: 1678-8060UDK: 579.852.13OceCobissID: 524801817COBISS_ID: 512578616DOI: 10.1590/0074-02760150294ISSN pri članku: 1678-8060NUK URN: URN:SI:UM:DK:C7T3DH3Esl