Kardiotoksičnost in več-organska odpoved zaradi zastrupitve z valproatomLetonja, Mitja (Avtor) Petrovič, Danijel (Avtor) kardiotoksičnostvečorganska odpovedvalproatWe report the case of severe valproate intoxication presenting as multiorgan failure. This is the first report to describe severe cardiac involvement, in which a 19-year-old woman developed atrial fibrillation, diffuse T wave inversion and QT c interval prolongation with elevated specific biochemical markers of myocardial damage. After 7 days of treatment, including supportive care, gas tric lavage, activated charcoal, mannitol and hemodialysis, the patient recovered completely . After the poisoning there were no patho- logical echocardiographic changes and one month after discharge exercise stress testing did not provoke ischemia or arrhythmias.20092024-04-19 08:53:12Znanstveno delo88379UDK: 615.9COBISS_ID: 26384345ISSN pri članku: 1855-5640sl