Henoch-Schönleinova purpura pri odraslemSkačej, Helena (Avtor) Holc, Iztok (Avtor) Pahor, Artur (Avtor) sistemski vaskulitisHenoch-Schönleinova purpuraodrasli bolnikBackground: Henoch-Schonlein purpura (HSP) is a systemic inflammation of small-vessel walls that predominantly affects children. In adults, on the other hand, it appears rarely, and can be more severe. The disease is characterised by a tetrad of clinical signs which manifest the skin, joint, gastrointestinal, and kidney involvement. HSP is diagnosed using internationally-accepted criteria. At present, there is no effective specific therapy for children and adults. However, in cases of severe organ involvement, aggressive treatment may stabilise the disease. Case report: We present a case of a 59-year-old immunologically uncom- promised patient with an extremely severe form of HSP. Epidemiology, etiopathogenesis, clinical features, diagnostic procedures, differential diagnosis, treatment, and prognosis of the disease are discussed. Conclusions: The patient was treated with corticosteroids, human polyspecific immunoglobulins, and immunosuppressive agents. A satisfactory clinical remission has been achieved.20092024-04-19 09:00:31Znanstveno delo88381UDK: 616.1-002COBISS_ID: 3494975ISSN pri članku: 1855-5640sl