20.500.12556/DKUM-30841 Stability of ranked gene lists in large microarray analysis studies This paper presents an empirical study that aims to explain the relationship between the number of samples and stability of different gene selection techniques for microarray datasets. Unlike other similar studies where number of genes in a ranked gene list is variable, this study uses an alternative approach where stability is observed at different number of samples that are used for gene selection. Three different metrics of stability, including a novel metric in bioinformatics, were used to estimate the stability of the ranked gene lists. Results of this study demonstrate that the univariate selection methods produce significantly more stable ranked gene lists than themultivariate selection methods used in this study. More specifically, thousands of samples are needed for these multivariate selection methods to achieve the same level of stability any given univariate selection method can achieve with only hundreds. gene selection techniques microarray analysis studies tehnike selekcije genov mikromreža analitične študije true false true Angleški jezik Slovenski jezik Znanstveno delo 2012-06-05 09:04:00 2012-06-05 09:04:00 2022-04-18 14:03:57 2021-04-13 03:17:39 2010 0 0 str. 1-9 Letn. 2010 2010 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 1110-7243 004.8:575 25780697 1615268 10.1155/2010/616358 1110-7243 URN:SI:UM:DK:EJDX3NDN Journal_of_Biomedicine_and_Biotechnology_2010_Stiglic,_Kokol_Stability_of_Ranked_Gene_Lists_in_Large_Microarray_Analysis_Studies.pdf Journal_of_Biomedicine_and_Biotechnology_2010_Stiglic,_Kokol_Stability_of_Ranked_Gene_Lists_in_Large_Microarray_Analysis_Studies.pdf 1 8E8DA45D7193174D520C763A79CAE698 f74edcbc4aec5cdc959d4e551fcf2d9142b805335532532916b246a8cc80d40d 3e597fa5-7c0e-11eb-bb7a-00155d0001ca 20.500.12556/dkum/d3101b42-c9de-4202-9762-a4ef279fb518 https://dk.um.si/Dokument.php?lang=slv&id=112529 http://www.hindawi.com/journals/bmri/2010/616358/ 1 https://dk.um.si/Dokument.php?lang=slv&id=41126 Fakulteta za zdravstvene vede 0 0 0