20.500.12556/DKUM-42720 VPLIV MIKROBIOTE KEFIRNIH ZRN NA PREŽIVETJE IN RAST GLIVE Candida albicans V MLEKU The influence of microbiota of kefir grains on the survival and growth of the fungus Candida albicans in milk V zadnjih dveh desetletjih se vedno več pojavlja invazivna glivična okužba, imenovana kandidoza, ki predstavlja velik zdravstveni problem po celem svetu. Za preprečevanje in zdravljenje kandidoze je med drugim potrebna tudi pravilna prehrana, med katero lahko uvrščamo tudi kefir. Tako smo se posledično v diplomskem delu osredotočili na vpliv kefirja na rast in razmnoževanje glive Candida albicans. Diplomsko delo je sestavljeno iz dveh delov; teoretičnega in raziskovalnega. V teoretičnem delu je predstavljena gliva C. albicans ter bolezni, ki jih povzroča. Opisali smo tudi kefir in njegovo sestavo, med katero sodijo kefirna zrna in kefiran. Splošno smo opisali tudi skupino probiotikov. V raziskovalnem diplomskem delu smo ugotavljali, kako se gliva kvasovka Candida albicans razmnožuje in raste v kulturi kefirnih zrn ali v svežem mleku. Različne koncentracije C. albicans smo gojili na Hicrome Ogye gojišču, kjer je bilo prisotno sveže mleko ali sveže mleko s kefirnimi zrni. Na podlagi raziskovalnega dela smo potrdili hipotezo, da smo ob prisotnosti kefirnih zrn zasledili manjšo rast kolonij C. albicans kot pa v svežem mleku. Iz tega lahko sklepamo, da kefir zavira oz. omejuje rast C. albicans. In the past two decades we have been noticing an increased manifestation of an invasive yeast infection candidiasis, which presents a huge health problem all over the world. In order to prevent and heal candidiasis, we should also consider a healthy diet that includes kefir as well. Therefore, this diploma thesis focuses on the influence of kefir on the growth and reproduction of Candida albicans. The diploma thesis consists of two parts, theoretical and empirical part. In the theoretical part, we presented the fungus C. albicans and diseases caused by it. We have also described kefir and its composition, which consists of kefir grains and kefiran. A general description of a group of probiotics is also given in that part of the diploma thesis. In the empirical part, we investigated in what way yeasts belonging to the culture of Candida albicans reproduce and grow in the culture of kefir grains or in fresh milk. Different concentrations of species C. albicans were cultured on Hicrome Ogye medium, with a presence of fresh milk or fresh milk including kefir grains. Based on the empirical part, we confirmed our hypothesis related to the influence of kefir on the growth of the yeast-like fungus C. albicans. In the presence of kefir grains, we detected the reduced growth of C. albicans colonies. This leads us to the conclusion that kefir prevents or inhibits the growth of C. albicans. kefirna zrna kefir simbioza Candida albicans mikrobiota kefirnih zrn glive kvasovke kefir grains kefir symbiosis Candida albicans microbiota of kefir grains yeasts true true false [M. Trunk] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2013-10-08 22:09:00 2013-10-22 08:58:36 2022-05-08 03:05:36 2021-04-27 03:37:02 2013 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 561.28(043.2) 1947812 URN:SI:UM:DK:JFU9G7MV VS_Trunk_Mateja_2013.pdf VS_Trunk_Mateja_2013.pdf 1 878AEEC12DBE00ACCFADCA0128BFC48E 2342f4b11d49f2874eab884bb321c420dd4e7b401a7b2a718dc0800e9d77ff92 7a91d0d3-7c0a-11eb-bb7a-00155d0001ca https://dk.um.si/Dokument.php?lang=slv&id=59987 Fakulteta za zdravstvene vede 0 0 0