20.500.12556/DKUM-52142 Treatment of movement disorders using deep brain stimulation - illustrative case reports and technical notes Stimulacija globokih možganskih jeder za zdravljenje motenj gibanja - prikaz primerov in tehničnih izboljšav Operative neuromodulation is the field of electrically or chemically altering the signal transmission in the nervous system by implanted devices in order to excite, inhibit or tune the activities of neurons or neural networks to produce therapeutic effects. Deep brain stimulation (DBS) is an important component of the therapy of movement disorders and has almost completely replaced high-frequency coagulation of brain tissue in stereotactic neurosurgery. This article presents the first DBS cases in Slovenia. In the article the technical features and adjustments of magnetic resonance (MR) imaging and development of a new microdrive, which was clinically successfully tested, are described and discussed. Operacijska nevromodulacija je reverzibilna uporaba električne stimulacije ali dovajanje farmakoloških snovi v osrednji živčni sistem z vgradnjo naprave v bolnikov telo. Namen je spreminjati aktivnost živčnega sistema (ekscitacija, inhibicija ali prilagajanje nevronov ali nevronske mreže) za zdravljenje specifičnih stanj. Globoka možganska stimulacija (GMS) je pomembna metoda za zdravljenje gibalnih motenj in je skoraj popolnoma nadomestila visokofrekvenčno koagulacijo možganovine. V članku predstavljamo prve slovenske primere GMS. Predstavili smo tehnične posebnosti in prilagoditve pri uporabi magnetne resonance ter razvoj novega mikrovodila, ki smo ga uspešno klinično preizkusili. operative neuromodulation microdrive stereotaxy Parkinson’s disease MR imaging operativna nevromodulacija mikrovodilo stereotaksija Parkinsonova bolezen magnetna resonanca true false true Angleški jezik Slovenski jezik Znanstveno delo 2015-07-10 17:07:00 2015-07-10 17:07:00 2022-05-31 03:09:26 2021-05-10 03:10:45 2012 0 0 str. 422-434 št. 5 Letn. 81 maj 2012 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 1318-0347 616.858-089 32893696 4294975 1318-0347 URN:SI:UM:DK:FEYO2ZBO Zdravniski_vestnik_2012_Strojnik,_Flisar,_Drstvensek_Treatment_of_movement_disorders_using_deep_brain_stimulation_-_illustrative_case_re.pdf Zdravniski_vestnik_2012_Strojnik,_Flisar,_Drstvensek_Treatment_of_movement_disorders_using_deep_brain_stimulation_-_illustrative_case_re.pdf 1 D07360586EC8756F4331509450DDE1A0 006a6d66efe087dc88c692e4341a0512aee8a19cfc2c0831ef259ef96830e718 0814a6b2-7c0e-11eb-bb7a-00155d0001ca https://dk.um.si/Dokument.php?lang=slv&id=110279 http://vestnik.szd.si/index.php/ZdravVest/article/view/803 1 https://dk.um.si/Dokument.php?lang=slv&id=110278 Fakulteta za strojništvo 0 0 0