20.500.12556/DKUM-52317-fbdd2501-d3f9-2c5b-9a07-2511d31f39ab Ali holecistektomija vpliva na Oddijev sfinkter in ampulo papile Vateri? Does cholecystectomy affect the sphincter of Oddi and the ampulla of Vater? Purpose: About 20-50% of cholecystectomized patients complain of dyspeptic problems after gallstone surgery. I hypothesized that some of these problems do not arise from primary gallbladder disease, but are due to problems of duodenal origin. Methods: I examined 80 patients using endoscopic ultrasound (EUS) before gallstone surgery (AOP). I repeated the examination 3 months (POP3) and 6 months (POP6) after the surgery. Fifty patients who underwent surgery were symptomatic; 30 were asymptomatic. In all patients, an analysis of the papilla of Vater (PV) was carried out with a special focus on the visibility of the sphincter of Oddi complex (SOC) and the ampulla of papilla (AP). Results: The visibility of the SOC was significant in the measurements AOP/POP3 (p<0.05). The comparison POP3/POP6 (p<0.001) was also significant. The behavior pattern of the AP (AOP/POP3, POP3/POP6, AOP/POP6) in various measurements was not significant (p>0.05). The linear percentage increase of non-visible AP (76%, 78%, and 80%) indicated different changes in the mechanism with respect to visibility of the SOC; 52% (AOP), 72% (POP3) and 50% (POP6). Conclusions: These data showed that cholecystectomy affected the visibility of the SOC. The AP, with its embryological and histological disposition based on a duodenal pattern (SOC is based on a biliary pattern), showed non-significant linear trends of increased non-visibility. Namen: Ker ima 20-50 % holecistektomirancev tudi po operaciji žolčnih kamnov nadaljnje dispeptične težave, želim dokazati, da del teh težav ne izvira iz primarne bolezni žolčnika s kamni, ampak so drugega, natančneje duodenalnega izvora. Metode: Z endoskopskim ultrazvokom (EUZ) sem pred operacijo (AOP) žolčnih kamnov pregledal 80 bolnikov. Tri mesece po operaciji (POP3) in 6 mesecev po njej (POP6) sem preiskavo ponovil. 50 operirancev je bilo simptomatskih, 30 pooperativno asimptomatskih. Pri vseh sem opravil analizo papile Vateri (PV) s posebnim poudarkom na analizi vidljivosti sfinkterja Oddi kompleksa (SOK) in ampule papile (AP). Rezultati: Vidljivost SOK je signifikantna v meritvah AOP/POP3 (p < 0.05) iz prikazanih sprememb. Prav tako je signifikantna primerjava POP3/POP6 (p < 0.001). Vzorec obnašanja AP (AOP/ POP3, POP3/POP6, AOP/POP6) v različnih meritvah ni signifikanten (p > 0.05). Linearno zvečanje odstotka nevidnih AP (76 %, 78 %, 80 %) kaže na druge mehanizme sprememb, kot sem jih ugotovil pri vidljivosti SOK 52 % (AOP), 72 % (POP3) in 50 % (POP6). Zaključek: Holecistektomija očitno deluje incidentalno na vidljivost SOK. To potrjujejo klinične izkušnje v potrebnem rekonvalenscentnem dietetnem režimu nekaj mesecev po operaciji, ki so potrebne za reprogramiranje SOK-a . AP, ki se obnaša po svoji embrionalni in histološki zasnovi po duodenalnem vzorcu (SOK po biliarnem), pa kaže počasne nesignifikantne linearne trende zvišane nevidljivosti. papila Vateri sfinkter Oddi holecistektomija endoskopski ultrazvok papilla of Vater sphincter of Oddi cholecystectomy endoscopic ultrasound true true false Medicinska fakulteta Angleški jezik Slovenski jezik Znanstveno delo 2015-07-10 17:24:22 2015-07-10 17:24:22 2026-03-19 14:07:58 2019-07-11 07:41:50 2011 0 0 str. 24-33 št. 1 Letn. 4 2011 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2011-01-01 616.366-003.7-072.16 242526720 512121144 1855-5640 URN:SI:UM:DK:CSX0HZKY http://www.dlib.si/details/URN:NBN:SI:doc-1MA0D6CG 1 https://dk.um.si/Dokument.php?lang=slv&id=76877 02.pdf 02.pdf 1 FD7DFF43CC2D74F4CEFA1C177F07763C 31e627ec05848a9fea212dcfcfdff8c7a7869526abea05516cd53adf46c8cdab 58efad89-fbbf-11ee-8eee-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=178597 Medicinska fakulteta Acta medico-biotechnica 0 0 0