20.500.12556/DKUM-54041 Primerjava različnih modelov pri sublimacijskem sušenju Comparison of different physical models in freeze drying processes Liofilizacija je postopek, pri katerem preko poznavanja trojne točke izvedemo postopek sušenja s pomočjo sublimacije. Postopek je danes veliko v uporabi v živilski in farmacevtski industriji, saj tekom izvedbe hrana oziroma biološka tkiva ne izgubijo kvalitet, ki so jih imele v normalnem stanju. Ker pa je postopek drag, so nekatera podjetja izrazila željo po razvoju simulacijskega orodja, ki bi celoten proces uspel izračunati in tako preprečil nepotrebne stroške. V tem delu je opisano, na kakšen način je bilo simulacijsko orodje razvito. Podano je fizikalno ozadje procesa in pa različni modeli, ki ga morejo opisati. Ker v modelih nastopa veliko koeficientov je bilo potrebno preveriti, kateri imajo močan vpliv na rezultate preračuna. Na podlagi izrisanih grafov je bila narejena primerjava in podan rezultat. Zaradi večje uporabnosti programa je bil izdelan tudi uporabniški vmesnik, katerega nastanek je opisan. Lyophilisation is a drying process that uses the knowledge of the triple point of material to dry through sublimation. This process is nowadays used a lot, mostly in food and pharmaceutical industry, for, as it runs, the food and biological tissues don't lose qualities, that they used to have in the beginning. This procedure is expensive and for that reason some companies expressed a wish for a simulation tool, that would compute the process before the experiments and hence would get rid of unnecessary expenses. This work describes the development of such a tool. The physical background is written as well as different models with which the process can be described. In mathematical model there are plenty of coefficients that are necessary for computation and it has been a wish to test which one has the strongest influence on results. Different plots and comparisons were made and conclusions were drawn. At the end the user interface has been made for the software, since in that way it is more useful and gives more people ability to use it. Sublimacijsko sušenje liofilizacija primerjava modelov vpliv parametrov na izračun Lyophilisation comparison of different physical models influence of coefficients on results numerical model of lyophilisation true true false [O. Verhnjak] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2015-08-19 08:46:14 2015-10-27 08:19:35 2022-06-04 03:10:18 2021-05-09 03:27:37 2015 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 519.872:66.047.3.049.6(043.2) 19138070 URN:SI:UM:DK:L1DG6R9P UN_Verhnjak_Ozbej_2015.pdf UN_Verhnjak_Ozbej_2015.pdf 1 0167117FAC38D1926189B57D27153D76 1441f823e744c679e706d601ae14e506733af5746690c7737cd04da8c0cc55c1 13b815fa-7c07-11eb-bb7a-00155d0001ca https://dk.um.si/Dokument.php?lang=slv&id=79025 Fakulteta za strojništvo 0 0 0