20.500.12556/DKUM-55703 ANALIZA DINAMIČNIH FIZIOLOŠKIH ODZIVOV PRI NEINVAZIVNEM MERJENJU KRVNEGA TLAKA S PROTITLAČNO METODO PENAZ ANALYSIS OF DYNAMIC PHYSIOLOGICAL RESPONSES IN NON-INVASIVE BLOOD PRESSURE MEASUREMENT WITH PENAZ BACK PRESSURE METHOD Bolezni obtočil so glavni vzrok smrti v razvitih delih sveta. Obtočila so pod nadzorom avtonomnega živčevja, zato se preko monitoringa srca zagotovi pogled v avtonomno živčevje. Zgodnja preventivna intervencija s presejalnimi testi pomeni pravočasno zdravljenje in znižanje umrljivosti. Raziskovali smo, ali je mogoče z medicinsko opremo, ki je primarno namenjena neprekinjenemu monitoringu v bolnišničnem okolju, izvajati hitre dinamične provokacijske teste, ki bi nam služili kot presejalni testi. Hemodinamične spremenljivke smo zajemali s kontinuirano neinvazivno protitlačno Peňáz metodo merjenja krvnega tlaka. Okno v delovanje avtonomnega živčevja pa je predstavljala variabilnost frekvence srca (HRV). Na zdravih prostovoljcih smo izvajali dva tipa provokacijskih testov obtočil: Valsalva manever in pasivni dvig nog (PLR). Podatke smo analizirali z Matlab programskim orodjem. Na podlagi opazovanja vseh štirih faz Valsalva manevra smo ugotovili, da je oprema sposobna zabeležiti hiter dinamični odziv. PLR test pa je pokazal nekoliko manjšo občutljivost. Oprema bi ob zelo natančni standardizaciji lahko predstavljala orodje za presejalne teste. Circulatory diseases are the main cause of death in the developed world. Circulatory system is under control of the autonomic nervous system, therefore through the cardiovascular monitoring we get an insight into the autonomic nervous system. An early intervention with preventive screenings ensures timely treatment and reduces mortality. We researched whether it is possible to perform fast dynamic provocation tests with the equipment that is primarly meant for uninterrupted monitoring in a hospital environment, and use these tests as screening assays. Hemodynamic variables were determined by the continuous noninvasive Peňáz backpressure method of measuring blood pressure. Heart rate variability (HRV) provided a window into the functioning of the autonomic nervous system. Using healthy volunteers, we carried out two types of challenge tests of the circulatory system: Valsalva maneuver and passive leg raising (PLR). Data were analyzed using the Matlab software tool. Our findings show that the equipment is able to record fast dynamic response, as we observed all four phases of Valsalva maneuver. PLR test demonstrated slightly lower sensitivity. With precise standardization the equipment could be used as a tool to perform screening assays. neinvazivna diagnostika presejalni testi obtočila noninvasive diagnosis screening tests circulatory system true true false G. Zrim Slovenski jezik Angleški jezik Magistrsko delo/naloga 2015-12-16 14:12:32 2015-12-23 13:47:52 2022-06-10 03:07:59 2021-05-15 03:23:25 2015 0 [Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 612.1:616.12-07(043.2) 19402774 URN:SI:UM:DK:XNDTUKIC MAG_Zrim_Grega_2016.pdf MAG_Zrim_Grega_2016.pdf 1 AB09B2F07CFEA36A4B458A28C6719E6F ac6dc0c66dd032d854b55faa8a416f4e39b51eee6a825c85cc7b97e9d698bb6f db4a34f2-7c0b-11eb-bb7a-00155d0001ca https://dk.um.si/Dokument.php?lang=slv&id=85306 Fakulteta za elektrotehniko, računalništvo in informatiko 0 0 0