20.500.12556/DKUM-56020 Kronične levkemije Chronic leukemias Levkemije so redke rakaste novotvorbe krvotvornega tkiva, katerih značilnost je kopičenje enega klona nenormalnih in posledično nefunkcionalnih krvnih celic v kostnem mozgu in v krvi. Ker celice ne podležejo apoptozi, se kopičijo v kostnem mozgu, zaradi česar se pojavi slabokrvnost, nevtropenija in trombocitopenija. Glede na vrsto celic jih delimo v limfatične in mieloične, glede na razvojno stopnjo levkemičnih celic in potek bolezni pa v akutne (hitro potekajoče) in kronične (dolgotrajne). Namen sestavka je predstaviti štiri najpogostejše kronične levkemije: kronično mieloično levkemijo, ki spada med mieloproliferativne bolezni ter kronično limfocitno levkemijo, dlakastocelično levkemijo in prolimfocitno levkemijo, ki spadajo med limfoproliferativne bolezni. Leukemias are malignant neoplasms of the hematopoietic system. They are characterized by the accumulation of a malignant clone of cells in the bone marrow and blood, which are afunctional. These cells are resistant to apoptosis, so they proliferate excessively and become accumulated in the bone marrow, leading to anemia, neutropenia and thrombocytopenia. Certain types of leukemia appear only during childhood, others exclusively in adults. Leukemias can be classified regarding the cell line to myeloid and lymphoid leukemias, an regarding their maturity and course of the disease to acute and chronic forms. The aim of this article is to present four chronic leukemias: chronic myeloid leukemia, which belongs to myeloproliferative diseases, and chronic lymphocytic leukemia, hairy cell leukemia and prolymphocytic leukemia, which are lymphoproliferative diseases. true false false Slovenski jezik Angleški jezik Delo ni kategorizirano 2015-12-21 16:16:00 2015-12-21 16:16:01 2022-06-10 03:09:27 2019-07-11 09:29:59 2005 0 0 str. 33-41 št. 1 Letn. 44 2005 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.1 3390978 1954623 0025-8121 URN:SI:UM:DK:TGVN0YOA http://www.medrazgl.si/e107_files/public/datoteke/mr05_1_03.pdf 1 https://dk.um.si/Dokument.php?lang=slv&id=84153 Univerza v Mariboru 0 0 0