20.500.12556/DKUM-66187 Hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in patients with recurrent variceal hemorrhage Purpose.The purpose of this study was to determine the incidence and predictors of hepatic encephalopathy (HE) after transjugular intrahepatic portosystemic shunt (TIPS) and endoscopic therapy (ET) in the elective treatment of recurrent variceal hemorrhage. Methods. Seventy patients were treated with elective TIPS and fifty-six patients with ET. Median observation time was 46.28 months in the TIPS group and 42.31 months in the ET group. Results. 30 patients (42.8%) developed clinically evident portosystemic encephalopathy in TIPS group and 20 patients (35.6%) in ET group. The difference between the groups was not statistically significant (P=0.542; X2 test). The incidence of new or worsening portosystemic encephalopathy was 24.3% in TIPS group and 10.7% in ET group. Multivariate analysis showed that ET treatment (P=0.031), age of >65 years (P=0.022), pre-existing HE (P=0.045), and Childs class C (P=0.051) values were independent predictors for the occurrence of HE. Conclusions. Procedure related HE is a complication in a minority of patients treated with TIPS or ET. Patients with increased age, preexisting HE, and higher Child-Pugh score should be carefully observed after TIPS procedure because the risk of post-TIPS HE in these patients is higher. veins dilated veins rebleeding portacaval encephalopathy liver cirrhosis portal hypertension transjugular intrahepatic portosystemic shunt vene razširjene ponovna krvavitev portokavalna encefalopatija jetra ciroza portalna hipertenzija transjugularni intrahepatični portosistemski obvod true false true Angleški jezik Slovenski jezik Znanstveno delo 2017-06-14 10:59:03 2017-06-14 11:00:16 2022-07-10 03:06:45 2021-05-15 03:27:15 2013 0 0 str. 1-5 Letn. 2013 2013 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 1687-630X 616.36 4614207 4614463 10.1155/2013/398172 1687-630X URN:SI:UM:DK:S8YYQSGW Gastroenterology_Research_and_Practice_2013_Peter_et_al._Hepatic_Encephalopathy_after_Transjugular_Intrahepatic_Portosystemic_Shunt_in_P.pdf Gastroenterology_Research_and_Practice_2013_Peter_et_al._Hepatic_Encephalopathy_after_Transjugular_Intrahepatic_Portosystemic_Shunt_in_P.pdf 1 8CCA308CE7EF3BCEE279A2FCAD06EF9D d46e4579f5579ee4699f64821b2cf119ae300831b7c05572f642758d0b842567 3db4a522-7c0e-11eb-bb7a-00155d0001ca https://dk.um.si/Dokument.php?lang=slv&id=112502 http://www.hindawi.com/journals/grp/2013/398172/ 1 https://dk.um.si/Dokument.php?lang=slv&id=112501 Medicinska fakulteta 0 0 0