20.500.12556/DKUM-66516 Comorbidities and characteristics of coronary heart disease patients: their impact on health-related quality of life Background: Patients with coronary heart disease (CHD) commonly present with more than one comorbid condition, contributing to poorer health-related quality of life (HRQoL). The aim of our study was to identify the associations between HRQoL and patient characteristics, vascular comorbidities and anxiety/depression disorders. Methods: This observational study was conducted in 36 family medicine practices selected by random stratified sampling from all regions of Slovenia. HRQoL was assessed using the European Quality of Life - 5 Dimensions (EQ-5D) questionnaire and EQ Visual Analogue Scale (EQ-VAS). The associations between HRQoL and patient characteristics stratified by demographics, vascular comorbidities, health services used, their assessment of chronic illness care, and anxiety/depression disorders were identified by ordinal logistic regression and linear regression models. Results: The final sample included 423 CHD patients with a mean age of 68.0 ± SD 10.8 years; 35.2% were female. Mean EQ-VAS score was 58.6 ± SD 19.9 (median: 60 with interquartile range of 45–75), and mean EQ-5D index was 0.60 ± SD 0.19 (median: 0.56 with interquartile range of 0.41–0.76). The statistically significant predictors of a lower EQ-VAS score were higher family physician visit frequency, heart failure (HF) and anxiety/depression disorders (R² 0.240; F = 17.368; p < 0.001). The statistically significant predictor of better HRQoL, according to EQ-5D was higher patient education, whereas higher family physician visit frequency, HF and peripheral artery disease (PAD) were predictors of poorer HRQoL (Nagelkerke R 2 = 0.298; χ 2 = 148.151; p < 0.001). Conclusions: Results of our study reveal that comorbid conditions (HF and PAD), family physician visit frequency and years in education are significant predictors of HRQoL in Slovenian CHD patients. coronary heart disease patient health-related quality of life vascular comorbidities anxiety/depression disorders koronarna srčna bolezen kvaliteta življenja zdravje vaskularne pridružene motnje anksiozne/depresivne motnje true false true Angleški jezik Slovenski jezik Znanstveno delo 2017-06-29 12:24:41 2017-06-29 12:25:37 2022-07-11 03:07:26 2019-07-11 15:47:57 2016 0 2016 str. 1-12 Letn. 14 2016 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 1477-7525 616.12-009.17 2604820 512642360 10.1186/s12955-016-0560-1 1477-7525 URN:SI:UM:DK:NF33MW4D Health_and_Quality_of_Life_Outcomes_2016_Tusek-Bunc,_Petek_Comorbidities_and_characteristics_of_coronary_heart_disease_patients_their_im.pdf Health_and_Quality_of_Life_Outcomes_2016_Tusek-Bunc,_Petek_Comorbidities_and_characteristics_of_coronary_heart_disease_patients_their_im.pdf 1 D6821232249BF3564DB75B2E5F640394 c883df1582c5d91eece049ed46e698327708b4438b19998ee58a6a4f43578f96 526d9541-7c0e-11eb-bb7a-00155d0001ca https://dk.um.si/Dokument.php?lang=slv&id=113342 http://hqlo.biomedcentral.com/articles/10.1186/s12955-016-0560-1 1 https://dk.um.si/Dokument.php?lang=slv&id=113341 Medicinska fakulteta 0 0 0