20.500.12556/DKUM-66656 Determination of penicillamine by batch and flow-injection potentiometry with AgI-based sensor Određivanje penicilamina primjenom klasične i protočno-injekcijske potenciometrije Potentiometric determination of penicillamine (pen) is described based on a batch experiment and flow-injection analysis (FIA) using a chemical sensor with AgI-based membrane. The membrane was prepared by pressing silver salts (AgI, Ag2S) and powdered Teflon. This membrane was incorporated in a multipurpose electrode body for batch measurements, and in a tabular flow-through sensor body for FIA measurements. For batch measurements, the equilibrium potentials recorded with continuous addition of standard penicillamine solution were considered in relation to ▫$lg(c_pen/mol L^-1)$▫. Linear response with slope of 60 mV was obtained in the concentration range from 2.5 x ▫$10^5$▫ mol ▫$L^1$▫ to 1.8 x ▫$10^-2$▫mol ▫$L-1$▫. In using the tubular sensor with a membrane of the same coposition for FIA measurements, the linear response with slope of 59 mV was recorded in the concentration range from 1 x ▫$10^4$▫ mol ▫$L^1$▫ to 1 x ▫$10^-1$▫ mol ▫$L^-1$▫. The response of the applied chemical sensor to penicillamine (designated also as RSH) is explained by the formation of sparingly soluble RSAg in the reaction solution and/or the exposed surface of the sensor. The solubility product ▫$K_s(RSAg)$▫ was determined using experimental values recorded both by batch measurements and by the continuous-flow experiment. The mean value obtained by different measurements and using a membrane of the same composition is ▫$K_s(RSAg)$▫ = (1.4+-0.1) x ▫$10^-20$▫ mol ▫$L-2$▫). Opisano je potenciometrijsko određivanje penicilamina (pen) primjenom klasične potenciometrije i protočno-injekcijske analize (FIA) uporabom kemijskog senzora s membranom na osnovi AgI. Membrana, pripravljena prešanjem soli srebra (AgI, Ag2S) i Teflona u prahu, ugrađena je u višenamjensko tijelo elektrode za klasična potenciometrijska mjerenja, odnosno u tijelo protočnoga cjevastog detektora za FIA. Ravnotežni potencijali, zabilježeni pri uzastopnim dodatcima standardne otopine penicilamina kod klasične potenciometrije, stavljeni su u odnos prema ▫$lg(c_pen/mol L^-1)$▫. Linearni odziv s nagibom od 60 mV dobiven je u koncentracijskom području od 2.5 x ▫$10^5$▫ mol ▫$L^1$▫ do 1.8 x ▫$10^-2$▫mol ▫$L-1$▫. Pri uporabi cjevastog senzora s membranom istog sastava kod FIA-mjerenja zabilježen je linearni odziv s nagibom 59 mV u koncentracijskom području od 1 x ▫$10^4$▫ mol ▫$L^1$▫ do 1 x ▫$10^-1$▫ mol ▫$L^-1$▫. Odziv korištenog kemijskog senzora prema penicilaminu (označen i kao RSH) protumačen je nastajanjem težko topljivog RSAg u reakcijskoj otopini ili/i na izloženoj površini senzora. Na temelju eksperimentalnih vrijednosti zabilježenih pri mjerenjima primjenom klasične potenciometrije i eksperimenta s kontinuiranim protokom kroz cjevasti senzor određen je produkt topljivosti ▫$K_s(RSAg)$▫. Dobivena srednja vrijednost različitih mjerenja s membranom istog sastava jest: ▫$K_s(RSAg)$▫ = (1.4+-0.1) x ▫$10^-20$▫ mol ▫$L-2$▫). analytical chemistry batch potentiometry flow-injection analysis membrane electrode tubular sensors penicillamine analizna kemija direktna potenciometrija pretočno injekcijska analiza membranske elektrode cevni senzorji penicilamin true false true Angleški jezik Hrvaški jezik Delo ni kategorizirano 2017-07-05 09:55:33 2017-07-05 09:56:55 2022-08-01 13:00:53 2019-07-11 15:54:34 2000 0 0 str. 265-277 št. 1 Letn. 73 2000 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 0011-1643 543.257 22807 5204502 0011-1643 URN:SI:UM:DK:YTPWV4B3 Croatica_Chemica_Acta_2000_Radic,_Komljenovic,_Dobcnik_Determination_of_penicillamine_by_batch_and_flow-injection_potentiometry_with_AgI.pdf Croatica_Chemica_Acta_2000_Radic,_Komljenovic,_Dobcnik_Determination_of_penicillamine_by_batch_and_flow-injection_potentiometry_with_AgI.pdf 1 4031B198291A8172DFD2F8278C54A9BB 09fbed625f00f9f58bb56df27801fd9ab61e5d5063baa97b552a46c19fae0712 5b1980ef-7c0e-11eb-bb7a-00155d0001ca 20.500.12556/dkum/2b6b7b77-d9c0-46c5-95f2-5819e67632b8 https://dk.um.si/Dokument.php?lang=slv&id=113660 http://hrcak.srce.hr/132094 1 https://dk.um.si/Dokument.php?lang=slv&id=113659 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0