20.500.12556/DKUM-67136 Optimization of induction of mild therapeutic hypothermia with cold saline infusion a laboratory experiment Cold fluid infusions can be used to induce mild therapeutic hypothermia after cardiac arrest. Fluid temperature higher than 4°C can increase the volume of fluid needed, prolong the induction phase of hypothermia and thus contribute to complications. We performed a laboratory experiment with two objectives. The first objective was to analyze the effect of wrapping fluid bags in ice packs on the increase of fluid temperature with time in bags exposed to ambient conditions. The second objective was to quantify the effect of insulating venous tubing and adjusting flow rate on fluid temperature increase from bag to the level of an intravenous cannula during a simulated infusion. The temperature of fluid in bags wrapped in ice packs was significantly lower compared to controls at all time points during the 120 minutes observation. The temperature increase from the bag to the level of intravenous cannula was significantly lower for insulated tubing at all infusion rates (median temperature differences between bag and intravenous cannula were: 8.9, 4.8, 4.0, and 3.1°C, for non-insulated and 5.9, 3.05, 1.1, and 0.3°C, for insulated tubing, at infusion rates 10, 30, 60, and 100 mL/minute, respectively). The results from this study could potentially be used to decrease the volume of fluid infused when inducing mild hypothermia with an infusion of cold fluids. cardiac arrest intravenous infusion therapeutic hypothermia srčni zastoj intravenska infuzija terapevtska hipotermija true false true Angleški jezik Slovenski jezik Znanstveno delo 2017-08-03 10:42:03 2017-08-03 10:42:55 2022-08-01 13:35:32 2019-07-11 16:10:12 2015 0 0 str. 60-63 št. 4 Letn. 15 2015 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 1840-4812 616.127-005.8 5097535 512564280 10.17305/bjbms.2015.565 1840-4812 URN:SI:UM:DK:O0MKFPSK Bosnian_Journal_of_Basic_Medical_Sciences_2015_Fluher_et_al._Optimization_of_induction_of_mild_therapeutic_hypothermia_with_cold_saline.pdf Bosnian_Journal_of_Basic_Medical_Sciences_2015_Fluher_et_al._Optimization_of_induction_of_mild_therapeutic_hypothermia_with_cold_saline.pdf 1 A6D7110A2C6CE8253DE061E83BC45D6A ea1c77fb954e0891d6182eadb848195e0e22dede018f3552140ab09d57d8ddb5 78d255c2-7c0e-11eb-bb7a-00155d0001ca 20.500.12556/dkum/fd252c34-8a58-49ce-9d14-c9125ba15e49 https://dk.um.si/Dokument.php?lang=slv&id=114786 http://www.bjbms.org/ojs/index.php/bjbms/article/view/565 1 https://dk.um.si/Dokument.php?lang=slv&id=114785 Medicinska fakulteta 0 0 0