20.500.12556/DKUM-74419 Liofilizacija polžje sline diplomsko delo Snail slime lyophilization Polžja slina je zaradi svojih izjemnih učinkovin v farmacevtski industriji zelo cenjena surovina, vendar njena naravna sluzasta oblika pri izdelavi zdravil ni kaj prida uporabna. V tem diplomskem delu zato opisujemo postopek sušenja sline s procesom liofilizacije. Sušili smo po različnih protokolih, med katerimi je najboljše rezultate pokazal tisti, ki je potekal pri najvišji temperaturi primarnega sušenja in pod najvišjim tlakom, medtem ko sekundarno sušenje sploh ni bilo potrebno. Najhitreje se je osušila viala v sprednjem delu sušilne komore, zadnja pa centralno ležeča viala. Dobili smo suho porozno snov, katero smo s postopkom kriogene granulacije uspešno spremenili v prah. Snail slime is a highly valued raw material due to its exceptional active ingredients in the pharmaceutical industry. However, its natural mucus formulation is not very useful. So, in this diploma work, the process of snail slime lyophilization is described. We were drying through various protocols, among which the best results showed the one that took place at the highest temperature of primary drying and below the highest pressure, while secondary drying was not even necessary. The most rapidly dried was front vial and the last one was central vial. We have obtained a dry porous substance, which was successfully transformed into dust by the cryogenic granulation process. liofilizacija kriogena granulacija polžja slina lyophilization cryogenic granulation snail slime true true false [M. Mom] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2019-08-27 14:04:15 2019-09-18 12:17:08 2022-08-09 09:03:44 2020-02-22 03:10:01 2019 0 Maribor 0 Maribor VI, 48 str. 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 57.086.13:594.3(043.2) 23015446 URN:SI:UM:DK:XJRNM0JQ UN_Mom_Misela_2019.pdf UN_Mom_Misela_2019.pdf 1 DFA67BE1F256EA18CB1B25ED573EE2D0 a7248bf8cbf9720a4835f258eac6e2a79bf43082cce496487fab2b3ce5e7ea08 f4922fd2-7c10-11eb-bb7a-00155d0001ca 20.500.12556/dkum/63bcddf4-cdec-476c-b34c-de5d1de9df7d https://dk.um.si/Dokument.php?lang=slv&id=137787 Fakulteta za strojništvo 0 0 0