20.500.12556/DKUM-76050 Razvoj kompozitnega materiala s kanabidiolom in celulozo magistrsko delo Development of composite material with cannabidiol and cellulose Veliko žensk se med menstruacijo bori z menstrualnimi krči. Da bi pripomogli k rešitvi tega problema, želimo izdelati tampon, s kanabidiolom (CBD), kateri ima zelo velik potencial v zdravstvu. Poleg tega gre za naravno in biorazgradljivo spojino. Namreč veliko sintetičnih zdravil se nepravilno odlaga, kar ima na okolje negativen vpliv. Z nano-kapsulacijo smo poskušali ujeti CBD v liposome, saj ti izboljšajo absorpcijo kanabidola. Učinkovitost kapsulacije smo preverjali z FTIR spektroskopijo, meritvami velikosti delcev, elektronsko mikroskopijo in GC-MS analizno metodo. Rezultati so pokazali, da se je CBD ujel v liposome. Tako pripravljeno formulacijo smo nanesli neposredno na celulozna vlakna. Analiza je pokazala, da je funkcionaliziran celulozni vzorec antioksidativen, protimikroben in sposoben desorpcije CBD. Many women struggle with menstrual cramps during their periods. To help solve this problem, we want to produce a tampon with cannabidiol, which has very high potential in healthcare. It is also a natural and biodegradable compound. Namely, many synthetic drugs are improperly disposed of, which has a negative impact on the environment. By nano-encapsulation, we tried to capture the CBD in liposomes as these enhance the absorption of CBD droplets. The encapsulation efficiency was verified by FTIR spectroscopy, particle size measurements, electron microscopy and GC-MS analysis method. The results showed that CBD was trapped in liposomes. The same formulation was applied directly to the cellulose fibers. The analysis showed that the functionalized cellulose sample was antioxidative, antimicrobial and CBD desorptive. celulozna vlakna FTIR spektroskopija kapsulacija bioaktivnost magistrske naloge tampon CBD FTIR spectroscopy encapsulation bioactivity true true false [K. Vrezner] Slovenski jezik Angleški jezik Magistrsko delo/naloga 2020-04-10 13:59:49 2020-04-10 13:59:50 2022-08-09 12:03:17 2020-04-11 03:10:51 2020 0 Maribor 2020 Maribor X, 50 f. 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 677.64.017.86:582.630.1(043.2) 23118614 URN:SI:UM:DK:ULNSGZ6Y MAG_Vrezner_Kaja_2020.pdf MAG_Vrezner_Kaja_2020.pdf 1 EDA1F1E61DF2362C2179615F4BEA0F8B 839d208e9acec337e313375fdded18712ad57606792919add1e70a63de49d2a5 4176abe9-7c11-11eb-bb7a-00155d0001ca 20.500.12556/dkum/68fdac58-403d-4ef5-b2d2-1726206df36c https://dk.um.si/Dokument.php?lang=slv&id=141245 Fakulteta za strojništvo 0 0 0