20.500.12556/DKUM-77479 Vpliv temperature na izolacijo komponent industrijske konoplje diplomsko delo univerzitetnega študijskega programa I. stopnje Influence of temperature on the isolation of industrial hemp components Diplomsko delo ugotavlja vpliv termične obdelave rastline pred ekstrakcijo in termične obdelave ekstrakta, na pretvorbo kanabidiolne kisline - CBDA v kanabidiol - CBD. Namen je bil določiti, katera od dveh metod dela, privede do kakovostnejšega produkta oziroma večjega deleža CBD. V sklopu diplomskega dela smo uporabili metodo ultrazvočne ekstrakcije z uporabo topila izopropanola. Ekstrakt se je pridobil iz zmlete posušene industrijske konoplje. Temperaturna dekarboksilacije kanabidiolne kisline je bila pri 130 °C. Dobljen produkt v obliki konopljinega ekstrakta se je analiziral z metodo HPLC-MS. Rezultati analiz povedo, da je proces dekarboksilacije kot zaključni proces priprave konopljinega ekstrakta primernejši. Segrevanje ekstrakta povzroči 16-krat večjo pretvorbo CBDA v CBD in tako 12 % višjo končno koncentracijo CBD. Z raziskavo smo dokazali, da je proces dekarboksilacije kot zaključni proces priprave konopljinega ekstrakta primernejši. Tako smo dobili produkt višje kakovosti. The diploma thesis determines the influence of heat treatment of the plant before extraction and heat treatment of the extract on the conversion of cannabidiolic acid - CBDA into cannabidiol - CBD. The purpose was to determine which of the two methods of work lead to a higher quality product or a higher share of CBD. As part of the diploma work, we used the method of ultrasonic extraction using the solvent isopropanol. The extract was obtained from ground dried industrial hemp. The decarboxylation temperature of cannabidiolic acid was at 130 ° C. The resulting product in the form of hemp extract was analyzed by HPLC-MS. The results of the analyzes show that the decarboxylation process is more suitable as the final process of preparation of hemp extract. Heating the extract results in a 16-fold increase in CBDA to CBD conversion and thus a 12 % higher final CBD concentration. The research proved that the decarboxylation process is more suitable as the final process of preparation of hemp extract, thus getting a higher quality product. Industrijska konoplja konopljin ekstrakt ekstrakcija komponent kanabinoidi pretvorba CBDA v CBD dekarboksilacija : Industrial hemp hemp extract component extraction cannabinoids conversion of CBDA to CBD decarboxylation true true false [A. Zidarič] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2020-09-01 12:00:07 2020-10-09 07:10:05 2022-08-09 15:37:06 2020-10-15 03:21:12 2020 0 Maribor 0 Maribor VII, 18 f. 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 66.061.3:582.630.1(043.2) 32387587 URN:SI:UM:DK:WQU4ZCT2 UN_Zidaric_Andrej_2020.pdf UN_Zidaric_Andrej_2020.pdf 1 9BD685E47B6DB7189FA9E12484165E36 8fd3dcda7f7947c687958503ce79365f49efa5097a5e3d9bc20beaef1970a8af e778dc56-7c11-11eb-bb7a-00155d0001ca 20.500.12556/dkum/a64fa74d-703a-4182-9bbd-0092e31e3578 https://dk.um.si/Dokument.php?lang=slv&id=146513 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0