20.500.12556/DKUM-81485 Vpliv sojinih fitoestrogenov na človeško telo in pregled sojinih izdelkov na slovenskem trgu magistrsko delo Effects of soy phytoestrogens on the human body and an overview of soy products on the slovenian market Soja in tradicionalna sojina živila, kot so tofu, miso, sojina omaka in tempeh, že več tisočletij igrajo pomembno vlogo v prehrani mnogih azijskih držav. Zaradi domnevnih prehranskih in zdravstvenih koristi ter povečanega zanimanja za rastlinske beljakovine je v zadnjih letih soja postala priljubljena tudi v številnih državah na zahodu. Pozornosti zaradi potencialno preventivne vloge, proti danes najbolj razširjenim kroničnim boleznim (osteoporoza, srčno-žilne bolezni), hormonsko odvisni raki (rak prostate in rak na prsih), so v soji deležne fitoestrogene molekule. Varnost fitoestrogenov, njihovo delovanje in vpliv na ženski in moški hormonski sistem je predstavljeno v prvem sklopu naloge. V drugem delu naloge je s pomočjo literature in pregleda razpoložljivosti sojinih izdelkov na slovenskem trgu narejena ocena izpostavljenosti prebivalcev Slovenije fitoestrogenom. Ugotovitve nakazujejo, da sojini fitoestrogeni v prehranskih dopolnilih nimajo škodljivih učinkov na človeško telo, če so ti uživani v dnevnih odmerkih do 150 mg v obdobju največ treh let. Soja je prisotna v številnih kategorijah izdelkov, največ v nadomestkih mesa in mesnih izdelkov, ter mleka in mlečnih izdelkov. Prebivalci Slovenije so kljub veliki ponudbi sojinih izdelkov na slovenskem trgu, nizko izpostavljeni fitoestrogenom. Dnevni vnosi izoflavonov med slovensko populacijo dosegajo 1,4 mg. Soy and traditional soy foods such as tofu, miso, soy sauce and tempeh have been playing an important role in the diet of many Asian countries for thousands of years. Due to its alleged nutritional and health benefits and due to an increased interest in plant protein, soybeans have become popular in many Western countries in recent years. They are also known for their potentially preventive role against common chronic diseases (osteoporosis, cardiovascular disease) and hormone-dependent cancers (prostate cancer and breast cancer). The safety of phytoestrogens, their action and impact on the female and male hormonal systems are presented in the first part of the paper. In the second part of the paper, an exposure assessment of the population of Slovenia to phytoestrogens is made with a literature review and an overview of the availability of soy products on the Slovenian market. The findings suggest that soy phytoestrogens in dietary supplements have no harmful effects on the human body if consumed in daily doses of up to 150 mg for a maximum of three years. Soy is present in many food categories, mostly in meat and dairy alternatives. Despite the great variety of soy products on the Slovenian market, the population of Slovenia is exposed to phytoestrogens in values of not more than 1,4 mg per day. estrogenski receptor fitoestrogen genistein izoflavon soja estrogen receptor phytoestrogen genistein isoflavone soy true true false [N. Pečnik] Slovenski jezik Angleški jezik Magistrsko delo/naloga 2022-03-31 15:00:58 2022-06-02 09:44:13 2022-08-10 00:31:20 0000-00-00 00:00:00 2022 0 Maribor 0 Maribor IX, 80 str. 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 633.34:615.256.5:613.2(043)=163.6 110040067 MAG_Pecnik_Nika_2022.pdf MAG_Pecnik_Nika_2022.pdf 1 2ABE0A65BD22BE7DF11A1EBA3EC39D0C 41674d06b6e6a43dc9338e68330e510d1dd0228d62d56b6c67587e1c8e09fcfc 694b048a-c222-11ec-b7af-00155d000105 20.500.12556/dkum/74ad6d67-f9d9-43ae-83f5-07ae279f4bb3 https://dk.um.si/Dokument.php?lang=slv&id=157465 Fakulteta za kmetijstvo in biosistemske vede 0 0 0