20.500.12556/DKUM-81941 Akumulacija strižnih napetosti med transportom cepiva magistrsko delo Accumulation of shear stresses during vaccine transport V magistrski nalogi je bilo izvedeno modeliranje večfaznega toka na podlagi volumskih sil, ki delujejo na tekočine med gibanjem. V obeh simulacijah je bil cilj ugotoviti količino akumuliranih strižnih napetosti v tekočini. V prvi simulaciji smo ugotavljali količino akumuliranih strižnih napetosti v kapljevini, ko se ta giblje v viali na laboratorijskem instrumentu, natančneje orbitalnem mešalniku (angl. orbital shaker). V drugi simulaciji je bil cilj enak, vendar je bila viala in s tem tudi tekočini, ki se nahajata v njem, izpostavljena določenemu režimu gibanja. Gibanje je bilo skladno s spektrom gibanja vozila, ki je predpisan v transportnem standardu ISTA 3A. Simulacije smo izvedli s pomočjo programa ANSYS FLUENT. Za pridobitev ustreznih vhodnih podatkov glede gibanja v primeru zasledovanja gibanja med transportom je bilo potrebno izvesti pretvorbo protokola gibanja iz PSD (Power Spectral Density) v pospešek tekočine, ki smo jo izvedli s pomočjo programske in numerične platforme MATLAB. In the master's thesis, modeling of a multiphase flow was performed based on the volumetric forces acting on the fluids during motion. In both simulations, the goal was to determine the amount of accumulated shear stress in the fluid. In the first simulation, we determined the amount of accumulated shear stress in the fluid as it moved in a vial on a laboratory device, specifically an orbital shaker. In the second simulation, the target was the same, but the vial, and thus the fluids within them, were subjected to a specific type of motion. The motion corresponded to the range of motion of the vehicle prescribed in the ISTA 3A transportation standard. The simulations were performed using the program ANSYS FLUENT. In order to obtain the appropriate input data for the motion in the case of motion tracking during transportation, it was necessary to perform the conversion of the motion protocol from PSD (Power Spectral Density) to fluid acceleration, which was done with the MATLAB software and numerical platform. biološka zdravila razpad beljakovin strižne napetosti akumulacija strižnih napetosti transport biological drugs protein degradation shear stresses shear stress accumulation transport true true false [J. Bertalanič] Slovenski jezik Angleški jezik Magistrsko delo/naloga 2022-06-20 18:59:47 2022-09-09 12:05:46 2023-05-10 03:05:26 0000-00-00 00:00:00 2022 0 Maribor 0 Maribor 1 spletni vir (1 datoteka PDF (XIII, 60 f.)) 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 615.81:531.226(043.2) 151363587 MAG_Bertalanic_Jan_2022.pdf MAG_Bertalanic_Jan_2022.pdf 1 5534E48FD506FB4289E87C8C0D3545E2 f3c6d8788c6d48f494e051167d48466721ad05bba8dd263facb4fdabfd3852bb c6ded895-2fa6-11ed-bbcc-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=162179 Fakulteta za strojništvo 0 0 0