20.500.12556/DKUM-81962 Brain dynamics underlying preserved cycling ability in patients with Parkinson’s disease and freezing of gait Parkinson’s disease (PD) is generally associated with abnormally increased beta band oscillations in the cortico-basal ganglia loop during walking. PD patients with freezing of gait (FOG) exhibit a more distinct, prolonged narrow band of beta oscillations that are locked to the initiation of movement at ∼18 Hz. Upon initiation of cycling movements, this oscillation has been reported to be weaker and rather brief in duration. Due to the suppression of the overall beta band power during cycling and its continuous nature of the movement, cycling is considered to be less demanding for cortical networks compared to walking, including reduced need for sensorimotor processing, and thus unimpaired continuous cycling motion. Furthermore, cycling has been considered one of the most efficient non-pharmacological therapies with an influence on the subthalamic nucleus (STN) beta rhythms implicative of the deep brain stimulation effects. In the current review, we provide an overview of the currently available studies and discuss the underlying mechanism of preserved cycling ability in relation to the FOG in PD patients. The mechanisms are presented in detail using a graphical scheme comparing cortical oscillations during walking and cycling in PD. gait freezing of gait Parkinson's disease cycling cortical oscillations beta band zamrznitev hoje Parkinsonova bolezen kolesarjenje kortikalne oscilacije beta območje motorične sposobnosti medicinska rehabilitacija telesna pripravljenost true false true Frontiers Research Foundation Angleški jezik Slovenski jezik Znanstveno delo 2022-06-23 07:39:36 2024-12-04 13:40:47 2024-12-05 03:10:33 0000-00-00 00:00:00 2022 0 0 Str. 1-6 št. članka 847703 Letn. 13 Jun. 2022 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2022-01-03 2022-05-20 2022-06-16 616.858:796.01 112226563 10.3389/fpsyg.2022.847703 1664-1078 Licen_2022_Brain_Dynamics_Underlying_Preserved.pdf Licen_2022_Brain_Dynamics_Underlying_Preserved.pdf 1 3AF952BC39541AE96E99B7BE18CA448F 6efbe2f222475b36b504a98e3bdbb10cd8fa3078879cb9515fbf38704c834a88 d9375095-b23c-11ef-8359-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=187089 https://doi.org/10.3389/fpsyg.2022.847703 1 de717731-f2b6-11ec-aabb-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=158840 Medicinska fakulteta 0 0 0