20.500.12556/DKUM-82604 Vpliv vitamina C na okužbo z virusom SARS-CoV-2 The effect of vitamin C on the infection with SARS-CoV-2 virus Uvod: Vitamin C je vodotopen vitamin, ki zaradi antioksidativnih sposobnosti pomaga imunskemu sistemu pri podpori celičnih funkcij. Covid-19 je bolezen, ki ga povzroča virus SARS-CoV-2. Ker le-ta povzroča blago do zmerno bolezen dihal, sepso, močan imunski odziv in oksidativni stres, je boj proti virusu kompleksno. V zaključnem delu smo želeli ugotoviti vpliv vitamina C na okužbo z virusom SARS-CoV-2. Metode: Uporabili smo krovni sistematični pregled literature z metodo pregleda, analize in sinteze znanstvene literature ter metodo kompilacije. S pomočjo PRISMA smernic smo lahko izvedli preglede člankov in jih kritično ocenili z JBI Systematic Review: Study selection and critical appraisal orodjem. Zbrane podatke smo po načinu tematske ocene analizirali in sintetizirali. Rezultati: Iz izbranih podatkovnih baz smo zbrali 645 zadetkov ter jih 21 uporabili za tematsko sintezo. Poudarili smo glavno temo: Vpliv vitamina C na okužbo z virusom SARS-CoV-2 in na podlagi teme izbrali podkategorije, iz katerih smo oblikovali proste kode. Razprava in sklep: Vitamin C bi morali vključevati v vsakodnevno prehrano, saj s svojimi koristnimi učinkovinami krepi imunski sistem in ščiti pljučni epitelij ter druge organe pred virusi. V visokih odmerkih je vitamin C varen in neškodljiv, saj je vodotopno mikrohranilo in se izloči iz telesa preko sečil. Introduction: Vitamin C is a water-soluble vitamin that, due to its antioxidant abilities, helps the immune system support cellular functions. Covid-19 is a disease caused by the SARS-CoV-2 virus. Because the SARS-CoV-2 virus causes mild to moderate respiratory disease, sepsis, a strong immune response, and oxidative stress, the fight against the virus is complex. With this diploma thesis we wished to determine the effect of vitamin C on the infection with SARS-CoV-2 virus. Methods: We used an umbrella systematic review of the literature with the method of review, analysis and synthesis of scientific literature, and the method of compilation. With the help of the PRISMA guidelines, we were able to review the articles and critically evaluate them with the JBI Systematic Review: Study selection and critical appraisal tool. The collected data were analysed and synthesized according to the method of thematic assessment. Results: From the selected databases, we collected 645 hits, and 21 of them were used for thematic synthesis. We emphasized the main topic: The effect of vitamin C on the infection with the SARS-CoV-2 virus and based on the topic, selected subcategories from which we created free codes. Discussion and conclusion: Vitamin C should be included in the daily diet, because with its beneficial agents, it strengthens the immune system and protects the lung epithelium, as well as other organs from viruses. In high doses, vitamin C is safe and harmless, as it is a water-soluble micronutrient is excreted from the body through the urinary tract. vitamin C SARS-CoV-2 okužba prognoza pregled vitamin C SARS-CoV-2 infection prognosis review true true false [K. Videnšek] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2022-08-26 09:43:12 2022-12-19 14:46:09 2023-01-23 15:34:38 0000-00-00 00:00:00 2022 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.98:578.834:577.164.2(043.2) 130247683 VS_Vidensek_Ksenja_2022.pdf VS_Vidensek_Ksenja_2022.pdf 1 8C83AB830F2611551E77BF95939B2875 aaf9eefefb5a26eb4fca977e7883fe9e9ac32fe10585ddf46acadf708675af46 9bc00dd9-2514-11ed-908c-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=160865 Fakulteta za zdravstvene vede 0 0 0