20.500.12556/DKUM-83347 Primerjava epiduralne analgezije in intravenske aplikacije remifentanila za lajšanje bolečine med porodom Comparison of epidural analgesia and intravenous use of remifentanil to relieve labour pain Uvod: Epiduralna analgezija in analgezija z intravensko aplikacijo remifentanila spadata med farmakološke oblike lajšanja porodne bolečine. Namen raziskave je primerjati lajšanje porodne bolečine med epiduralno analgezijo in intravensko aplikacijo remifentanila, saj predstavlja porod eno izmed hujših bolečin. Metode: V raziskavi smo uporabili kvantitativno metodo dela, izvedli smo primerjalno študijo, v kateri je sodelovalo 60 porodnic, ki so za lajšanje porodne bolečine izbrale epiduralno analgezijo ali infuzijo remifentanila. Ob lajšanju bolečine smo raziskali neželene učinke pri materi in otroku ter vpliv na dolžino in potek poroda. Podatke smo pridobili s pomočjo vnaprej pripravljenih obrazcev in jih obdelali v programu SPSS Statistics. Podatkom smo pred testiranjem preverili normalnost porazdelitve s pomočjo Shapiro Wilkov testa in uporabili neparametričen Mann-Whitney U-test, ki nam je podal informacijo ali je med raziskovanima skupinama prisotna statistično značilna razlika. Pri statističnem testu smo uporabili 5-odstotno stopnjo tveganja. Rezultati: Porodnice z epiduralno analgezijo ocenjujejo bolečino po lestvici VAS nižje kakor tiste, ki so izbrale intravensko aplikacijo remifentanila po 15 min (3,63 proti 6,63), 30 min po aplikaciji (1,90 prot 6,33) in ob iztisu (5,00 proti 7,17). Porod traja dalj časa pri porodnicah z epiduralno analgezijo, za katero se po večini odločijo prvorodke. Razlike v oceni APGAR otroka niso ugotovljene. V enakem številu se je porod končal z vaginalnim porodom (n = 27) in s carskim rezom (n = 3) pri obeh metodah. Neželeni učinki so bili ugotovljeni pri obeh metodah pri porodnici, pri otroku pa v minimalni pojavnosti. Razprava in sklep: Lajšanje bolečine z epiduralno analgezijo se je pokazalo za bolj učinkovito z manj neželenih učinkov. Obe metodi sta varni za porodnico in otroka. Introduction: Epidural analgesia and analgesia with intravenous administration of remifenatnil are pharmacological methods for labour pain relief. The purpose of the research is to compare the relief of labour pain among epidural analgesia and intravenous administration of remifentanil, as labour is one of the worst pains. Methods: In the research, we used a quantitative method of work, we conducted a comparative study in which 60 women participated, who chose epidural analgesia or remifentanil infusion to relieve labour pain. Along with pain relief, we investigated side effects in the mother and child, as well as the impact on the length and course of labour. We obtained the data with the help of pre-prepared forms and processed them in the SPSS Statistics program. Before testing the data, we checked the normality of the distribution using the Shapiro-Wilk test and used the non-parametric Mann-Whitney U test, which gave us information on whether there was a statistically significant difference between the investigated groups. A 5 % risk level was used in the statistical test. Results: Women in labour with epidural analgesia rate the pain according to the VAS scale lower than those who chose intravenous administration of remifentanil after 15 min (3.63 vs. 6.63), 30 min of application (1.90 vs. 6.33) and during delivery (5.00 vs. 7.17). Childbirth takes longer with epidural analgesia, which is usually chosen by first time mothers. No differences were found in the child's APGAR score. An equal number of deliveries ended with vaginal delivery (n = 27) and caesarean section (n = 3) in both methods. Adverse effects were found in both methods in the parturient woman, but in the child in minimal incidence. Discussion and conclusion: Pain relief with epidural analgesia has been shown to be more effective with fewer side effects. Both methods are safe for the mother and baby. Epiduralna analgezija remifentanil porodna bolečina Epidural analgesia remifentanil labour pain true true false [M. Grebenc] Slovenski jezik Angleški jezik Magistrsko delo/naloga 2022-10-30 16:25:48 2022-12-19 14:09:55 2023-01-03 15:42:31 0000-00-00 00:00:00 2022 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 618.414.4-089.5(043.2) 131555587 MAG_Grebenc_Martina_2022.pdf MAG_Grebenc_Martina_2022.pdf 1 6203A8EABB22C7A7B011DDC8391B7F4E da4fd34def434df0821b2e1b047d47f0bdea94ac6e1f5efd197f2aa18d5ab566 c1da4124-6aaa-11ed-b081-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=164508 Fakulteta za zdravstvene vede 0 0 0