20.500.12556/DKUM-84917 Vpliv probiotikov na respiratorne okužbe starejših posameznikov The effect of probiotics on respiratory infections in older people Akutne respiratorne okužbe so po vsem svetu splošno razširjen zdravstveni problem, z 90% smrtnostjo pri ljudeh, starejših od 65 let. Ker imunosenescenca vpliva na posameznikovo zdravje, izvajamo ukrepe za dvig imunskega sistema, kamor spada tudi uživanje probiotikov. Probiotiki so živi organizmi, katerih uporaba v zadostnih količinah ugodno vpliva na posameznikovo zdravje. Zaključno delo je temeljilo na opisni metodi dela, pregledano strokovno literaturo smo pridobili iz elektronskih baz CINAHL, PubMed, ScienceDirect. Pri tem smo upoštevali vključitvene in izključitvene kriterije ter sam potek iskanja literature prikazali z diagramom poteka po smernicah PRISMA. Za oceno kakovosti izbranih študij smo uporabili hierarhijo dokazov v osmih stopnjah. Opravili smo tematsko analizo in sintezo podatkov. Študije so pokazale, da so probiotiki lahko potencialen del pristopa k zaščiti pred respiratornimi okužbami starejših oseb. V študiji so z uporabo Lactiplantibacillus pentosus B240 znižali incidenco respiratornih okužb in z Lacticaseibacillus casei Shirota skrajšali čas trajanja same okužbe. Probiotiki imajo pozitiven vpliv na zdravje človeka, saj spodbudijo imunski sistem in proizvodnjo protimikrobnih peptidov, kratkoverižnih maščobnih kislin in drugih koristnih metabolitov. Uporaba probiotikov kot zaščite starejših oseb pred respiratornimi okužbami in pri lajšanju simptomatike le-teh ima lahko poleg kliničnega tudi ekonomski doprinos. Acute respiratory infections are a widespread health problem worldwide, with 90% of deaths occurring in people over 65 years of age. As immunosenescence affects the health of the individual, we take measures to boost the immune system, including taking probiotics. Probiotics are living organisms that, when used in adequate amounts, have a beneficial effect on an individual's health. The bachelors thesis was based on descriptive method, the reviewed literature was obtained from electronic databases CINAHL, PubMed, ScienceDirect. We took into account the inclusion and exclusion criteria and illustrated the literature search process with according to the PRISMA guidelines. To assess the quality of the selected studies, we used an 8-level hierarchy of evidence. Thematic analysis and data synthesis were carried out. Studies have shown that probiotics can be considered as a potential part of an approach to protect against respiratory infections. In the study, the use of Lactiplantibacillus pentosus B240 reduced the incidence of respiratory infections and Lacticaseibacillus casei Shirota reduced the duration of the infection itself. Probiotics have a positive impact on human health by stimulating the immune system and the production of antimicrobial peptides, short chain fatty acids and other beneficial metabolites. The use of probiotics to protect older people against and alleviate the symptoms of respiratory infections can have not only clinical but also economic benefits. probiotiki respiratorne okužbe starejše osebe probiotics respiratory infections older person true true false [M. Hajduk] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2023-08-08 15:14:13 2023-10-25 15:29:21 2024-01-04 15:48:02 0000-00-00 00:00:00 2023 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 613.292:616.2-053.9(043.2) 168343299 VS_Hajduk_Miha_2023.pdf VS_Hajduk_Miha_2023.pdf 1 1B208C860B01FCB6D5D72E28D15BBEED aa99d1c9b60f79afe3f6f6acd8b9c07b9778ac2ecaf623bc1e186b3662fe1f58 c23c849e-3d99-11ee-8efa-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=169724 Fakulteta za zdravstvene vede 0 0 0