20.500.12556/DKUM-85014 Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum an overview Ganoderma lucidum is a very medicinal mushroom that has been utilized in Oriental medicine for many years. It has a wide range of pharmacological and therapeutic properties, and has been used for many years as a health promoter. It contains various biologically active compounds that improve the immune system and have antioxidant, antitumor, anti-inflammatory, antifungal, and antimicrobial properties. Active compounds include triterpenoids and polysaccharides, as well as proteins, lipids, phenolics, sterols, etc. In the following review, we summarize briefly their biological activities, such as antioxidant, anti-bacterial, anti-fungal, antitumor, anti-viral, and anti-inflammatory activity. Although Ganoderma has a number of medicinal effects that have been confirmed by the in vitro and in vivo studies summarised in this review, there are some limitations. Clinical trials face mainly a lack of pure constituents. Accurate identification of the compounds obtained is also problematic. In addition, most of the included studies were small, and there were concerns about the methodological quality of each study. Studies have shown that Ganoderma has valuable potential for the prevention and treatment of cancer. In any case, G. lucidum cannot be used as first-line therapy for cancer. Ganoderma lucidum bioactive function active compounds polysaccharides triterpenoids bioaktivne funkcije aktivne sestavine polisaharidi true false true Frontiers Media Angleški jezik Slovenski jezik https://www.frontiersin.org/journals/pharmacology © 2022 Cör Andrejč, Knez and Knez Marevci Znanstveno delo 2023-08-16 09:41:12 2023-08-16 09:41:12 2024-12-09 07:51:55 0000-00-00 00:00:00 2022 0 0 14 str. Vol. 13 2022 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2022-05-03 2022-06-27 2022-07-22 577 116231939 10.3389/fphar.2022.934982 1663-9812 Antioxidant,_antibacterial,_antit-Andrejc-2022.pdf Antioxidant,_antibacterial,_antit-Andrejc-2022.pdf 1 82973125D6DED6DB688E44FE50715F0D 10d83f5c18e81e539780db781d77b6297529ea70bc20afe21c2cca182b06ca97 dcf899fb-3c08-11ee-b5e9-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=169541 https://www.frontiersin.org/articles/10.3389/fphar.2022.934982/full 1 4c033577-3c08-11ee-b5e9-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=169539 Fakulteta za kemijo in kemijsko tehnologijo Medicinska fakulteta 0 0 0