20.500.12556/DKUM-85227 Vpliv iducirane hipotermije ob nenadnem zastoju srca The effect of induced hypothermia in the event of sudden onset cardiac arrest Uvod: Inducirana oz. terapevtska hipotermija je nadzorovano znižanje telesne temperature v terapevtske namene in se priporoča kot standard pri zdravljenju pacientov v kritičnem stanju. Hipotermija izboljša preskrbo možganov z načinom zmanjšanja celičnega metabolizma in posledično zmanjšane potrebe po kisiku, kar daje pacientu boljše možnosti za pozitiven nevrološki izid zdravljenja. Namen zaključnega dela je raziskati vpliv inducirane hipotermije na nevrološki izid pri pacientih po preživelem nenadnem zastoju srca. Metode: Z namenom izdelave zaključnega dela smo v podatkovnih bazah PubMed, Science Direct in Cochrane Library poiskali raziskave, pri čemer smo si pomagali z iskalnim nizom in zastavljenimi omejitvami. Potek iskanja raziskav smo predstavili v PRISMA diagramu. Uporabljena je bila deskriptivna metoda dela. Rezultati: Inducirana ali terapevtska hipotermija izboljša nevrološki izid in okrevanje pacientov, ne glede na to, ali gre za bolnišnični ali izvenbolnišnični srčni zastoj. Inducirana hipotermija prav tako ni povezana s povečanjem smrtnosti in pojavom neželenih stranskih učinkov. Razprava in zaključek: Pacienti po preživelem nenadnem zastoju srca imajo s pomočjo moderne medicinske obravnave velike možnosti preživetja in izhoda z dobrim nevrološkim izidom zdravljenja. Inducirana hipotermija predstavlja način zdravljenja, ki bi moral postati standard v obravnavi akutno bolnega pacienta po preživelem zastoju srca, saj raziskave potrjujejo njeno učinkovitost. Introduction: Induced or therapeutic hypothermia is a controlled lowering of body temperature for therapeutic purposes and is recommended as a standard in the treatment of critically ill patients. Hypothermia improves the supply of the brain by reducing cellular metabolism and consequently reducing the need for oxygen, which gives the patient better chances for a positive neurological outcome of the treatment. The purpose of the final work is to investigate the impact of induced hypothermia on the neurological outcome in patients who have survived sudden cardiac arrest. Methods: In order to produce the final work, we searched for research in the PubMed, Science Direct and Cochrane Library databases, which was helped by the search string and set limitations. We presented the research search process in the PRISMA diagram. A descriptive method of work was used. Results: Induced or therapeutic hypothermia improves neurologic outcome and recovery in patients with in-hospital or out-of-hospital cardiac arrest. Induced hypothermia is also not associated with increased mortality and occurrence of unwanted side effects. Discussion and conclusion: With the help of modern medical treatment, patients who have survived sudden cardiac arrest have a high chance of survival and exit with a good neurological outcome of the treatment. Induced hypothermia represents a method of treatment that should become standard in the treatment of acutely ill patients after surviving cardiac arrest, as research confirms its effectiveness. hipotermija srčni zastoj zdravljenje nevrološki izid hypothermia cardiac arrest treatment neurological outcome true true false [F. Bračko] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2023-08-22 19:19:45 2023-10-13 13:47:43 2024-01-04 15:28:57 0000-00-00 00:00:00 2023 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.12-008.315:612.592(043.2) 165872899 VS_Bracko_Filip_2023.pdf VS_Bracko_Filip_2023.pdf 1 C1A861D8BD741B9B4757C3A0A1FFD1B8 c52e890cd53a34a754b0b5f54d1d3a95e550b900f3eb6269f598a59d5e46b1d7 7952c98b-41f5-11ee-9a51-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=170212 Fakulteta za zdravstvene vede 0 0 0