20.500.12556/DKUM-85301 Sinteza in karakterizacija amino funkcionaliziranega akrilamida kot prekurzorja za inteligentne polimere diplomsko delo univerzitetnega študijskega programa I. stopnje Synthesis and characterisation of amine functionalised acrylamide as precursor for smart polymers V tem diplomskem delu smo z nukleofilno acilno substitucijo sintetizirali funkcionalizirane akrilamide, ki so predstavljali osnovno monomerno enoto za nadaljno polimerizacijo. Reakcija sinteze monomerov je potekla med enim aminom in enim kislinskim kloridom. Za amine smo uporabljali etilen diamin (EDA), tris(2 aminoetil) amin (TAEA) ali bis(2-hidroksipropil) amin (BHPA), za kislinske kloride pa smo izbrali akriloil klorid (ACl) ali metakriloil klorid (MACl). Reaktante smo raztopili v topilu diklorometan (DCM), ob prisotnosti trietilamina (TEA). Nato smo produkte reakcij uporabili kot monomere pri prosti radikalski polimerizaciji. Polimerizacijo smo izvajali v masi ob prisotnosti termičnih iniciatorjev α,α' azobisizobutironitrila (AIBN) oziroma kalijevega peroksidisulfata (KPS). Uspešnost sinteze monomerov, torej kemijsko strukturo, smo preverili s pomočjo Fourierjeve transformacijske infrardeče spektroskopije (FTIR) in spektroskopije jedrske magnetne resonance (NMR), medtem ko smo polimere okarakterizirali s Fourierjevo transformacijsko infrardečo spektroskopijo. Produkti, ki so bili sintetizirani z metakriloil kloridom so se izkazali za uspešne pri sintezi monomerov in tudi pri polimerizaciji. Nadaljni razvoj takšnih materialov bi ogromno doprinesel na področju bioloških aplikacij, predvsem pri celičnem inženiringu in na področju odzivnih materialov. In this thesis, functionalized acrylamides were synthesised by nucleophilic acyl substitution to form the basic monomeric unit for polymerisation. The monomer synthesis reaction took place between one amine and one acid chloride molecule. Ethylene diamine (EDA), tris(2 aminoethyl) amine (TAEA) and bis(2-hydroxypropyl) amine (BHPA) were used as amines, while acryloyl chloride (ACl) and methacryloyl chloride (MACl) as acid chlorides. Reactants were dissolved in dichloromethane (DCM) solvent in the presence of triethylamine (TEA) and the reaction products were used as monomers in free radical polymerisation. The polymerisation was carried out in the presence of thermal initiators α,α' azobisisobutyronitrile (AIBN) or potassium peroxydisulfate (KPS). The success of the monomer synthesis, chemical structure, was verified by Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance spectroscopy (NMR), while the chemical structure of the polymers was characterised by Fourier ¬¬transform infrared spectroscopy. The products synthesised with methacryloyl chloride have proven successful in both monomer synthesis and polymerisation. The further development of such materials would make an important contribution to the field of biological applications of responsive polymers, especially in tissue engineering and as responsive materials. amino funkcionaliziran akrilamid nukleofilna substitucija radikalska polimerizacija polimeri FTIR NMR amino functionalized acrylamide nucleophilic substitution radical polymerisation polymers FTIR NMR true true false [K. Kogal] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2023-08-24 22:34:52 2023-09-04 11:56:32 2023-09-08 03:05:59 0000-00-00 00:00:00 2023 0 Maribor 0 Maribor 1 spletni vir (1 datoteka PDF (XI, 35 f.)) 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 66.095.26(043.2) 163556355 UN_Kogal_Kaja_2023.pdf UN_Kogal_Kaja_2023.pdf 1 1B51C887A4C02EFAF00E18F3051FFFFC 40c637add1b3c832f317331214bb9f06d49f1450f60fa7fd418e2988a023429a c1d1ac5a-48d8-11ee-b9d2-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=171225 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0