20.500.12556/DKUM-87027 The dose–response relationship of quercetin on the motor unit firing patterns and contractile properties of muscle in men and women Quercetin is one type of ergogenic aid and its effects on the neuromuscular system have recently attracted interest, but its dose-effect is not yet fully understood. The aim of this study was to examine the effect of different doses of quercetin ingestion on motor unit firing patterns and muscle contractile properties in humans. Thirteen young males and females conducted neuromuscular performance tests before (PRE) and 60 min after (POST) ingestions of 500 or 200 mg of quercetin glycosides (Qg500/Qg200, respectively) or placebo (PLA) on three different days. At PRE and POST, motor unit firing rates were calculated from high-density surface electromyography of the vastus lateralis muscle during 120-s isometric contraction of knee extension at 10% of maximal voluntary contraction. Electrically elicited forces in knee extensor muscles were also measured. After 60 s of voluntary contraction, motor unit firing rates, normalized by the exerted muscle force at POST, were significantly lower at POST than PRE with Qg500 and Qg200 (p < 0.05), but not with PLA (p > 0.05). Changes in motor unit firing rates normalized by the exerted force from PRE to POST were significantly greater with Qg500 than Qg200 at the end of contraction (p < 0.05). Under all three conditions, the electrically elicited force did not significantly change from PRE to POST (p > 0.05). These results suggest that both 500 and 200-mg quercetin ingestions alter motor unit firing patterns, and that quercetin’s effect is at least partially dose-dependent. ergogenic aids nutritional supplementation multichannel surface electromyography motor unit identification quercetin prehranska dopolnila elektromiografija motorične enote kvercetin true false true Taylor & Francis, BioMed Central Angleški jezik Slovenski jezik https://www.tandfonline.com/journals/rssn20 © 2023 The Author(s) Članek v reviji 2024-02-09 10:19:54 2024-02-09 10:32:26 2024-06-10 12:39:19 0000-00-00 00:00:00 2023 0 0 Str. 823-836 Št. 1, št. članka 2265140 Letn. 20 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2022-03-23 2023-09-26 2023-10-03 613.2:591.131.1 170741763 10.1080/15502783.2023.2265140 1550-2783 Watanabe-2023-The_dose-response_relationship_o.pdf Watanabe-2023-The_dose-response_relationship_o.pdf 1 A37DD1E4AA8859EFFD9DD208C3F693F7 4a7b3061129c9662683fc63a325181f58cf586de785ba29056fa633bc0b0fcea e003c99a-c72d-11ee-a1af-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=176032 https://www.tandfonline.com/doi/full/10.1080/15502783.2023.2265140 0 023e3e0c-c72e-11ee-a1af-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=176033 Fakulteta za elektrotehniko, računalništvo in informatiko 0 0 0