20.500.12556/DKUM-87044 Safety and feasibility of vulvar cancer treatment with electrochemotherapy A prospective institutional study was conducted at the Institute of Oncology in Ljubljana. The main objective of the study is to determine the safety and feasibility of electrochemotherapy in the treatment of vulvar cancer recurrence. From July 2020 to January 2023, 10 patients with vulvar cancer recurrence were enrolled in our study. Patients were treated with an intravenous application of bleomycin, and 8 min later, electric pulses were applied locally to the tumor to increase the cytotoxicity of bleomycin. The treatment could be performed in all patients, demonstrating its feasibility, and no adverse effects were documented, proving that the treatment is safe. In conclusion, this is the first prospective study of electrochemotherapy in the treatment of local vulvar cancer recurrence conducted for nonpalliative purposes, demonstrating its safety and feasibility. electroporation vulvar cancer electrochemotherapy elektroporacija rak elektrokemoterapija true false true MDPI Angleški jezik Slovenski jezik Znanstveno delo 2024-02-12 14:58:48 2024-02-12 15:11:36 2024-02-13 03:09:47 0000-00-00 00:00:00 2023 0 0 Str. 1-12 Št. 12, št. članka 3079 Letn. 15 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2023-05-16 2023-06-05 2023-06-07 618.1 154827267 10.3390/cancers15123079 2072-6694 Vivod-2023-Safety_and_Feasibility_of_Vulvar_Ca.pdf Vivod-2023-Safety_and_Feasibility_of_Vulvar_Ca.pdf 1 F2DE7F8E91055A0B3FDC23632D004357 7c878d262f7bbc52c67b2ea3f31f61d36746ff6a7b0634bcfa1f225b8f4b6866 7579d6ac-c9b0-11ee-97b9-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=176092 https://doi.org/10.3390/cancers15123079 0 d8e482f9-c9ae-11ee-97b9-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=176091 Medicinska fakulteta 0 0 0