20.500.12556/DKUM-87383 Urinary metabolic biomarker profiling for cancer diagnosis by terahertz spectroscopy review and perspective In the last decade, terahertz (THz) technologies have been introduced to the detection, identification, and quantification of biomolecules in various biological samples. This review focuses on substances that represent important biomarkers in the urine associated with various cancers and their treatments. From a diagnostic point of view, urine liquid biopsy is particularly important because it allows the non-invasive and rapid collection of large volumes of samples. In this review, the THz spectral responses of substances considered metabolic biomarkers in urine and obtained in previous studies are collected. In addition, the findings from the relatively small number of prior studies that have already been carried out on urine samples are summarised. In this context, we also present the different THz methods used for urine analysis. Finally, a brief discussion is given, presenting perspectives for future research in this field, interpreted based on the results of previous studies. This work provides important information on the further application of THz techniques in biomedicine for detecting and monitoring urinary biomarkers for various diseases, including cancer. terahertz spectroscopy urinary biomarkers metabolic biomarkers cancer diagnostics biomolecules non-invasive detection biomedical detection terahertz spektroskopija urinski biomarkerji metabolni biomarkerji diagnostika raka biomolekule neinvazivno odkrivanje biomedicinsko odkrivanje true false true MDPI Angleški jezik Slovenski jezik Znanstveno delo 2024-03-14 09:48:28 2024-03-14 10:12:17 2024-03-15 03:17:00 0000-00-00 00:00:00 2023 0 0 Str. 1-36 Št. 9, št. članka 1051 Letn. 10 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2023-07-31 2023-09-12 2023-09-15 577 164724483 doi.org/10.3390/photonics10091051 2304-6732 Abina-2023-Urinary_Metabolic_Biomarker_Profili.pdf Abina-2023-Urinary_Metabolic_Biomarker_Profili.pdf 1 4EB2C464969F02A1562A76FDDFA6AAD0 f0edb24d6dac45882f0b0fb1b8a10e699621c25780287e971979425be9549c8a b7fec989-e1e2-11ee-8231-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=176875 https://doi.org/10.3390/photonics10091051 0 a35ad22d-e1df-11ee-8231-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=176873 Fakulteta za naravoslovje in matematiko 0 0 0