20.500.12556/DKUM-87398 Helichrysum italicum From Extraction, Distillation, and Encapsulation Techniques to Beneficial Health Effects Helichrysum italicum (family Asteraceae), due to its various beneficial health effects, represents an important plant in the traditional medicine of Mediterranean countries. Currently, there is a renewed interest in this medicinal plant, especially in investigations involving the isolation and identification of its bioactive compounds from extracts and essential oils, as well as in experimental validation of their pharmacological activities. In this paper, we review the current knowledge on the beneficial health effects of Helichrysum italicum extracts, essential oils, and their major bioactive polyphenolic compounds, ranging from antioxidative, anti-inflammatory, and anticarcinogenic activities to their antiviral, antimicrobial, insecticidal, and antiparasitic effects. This review also provides an overview of the most promising extraction and distillation techniques for obtaining high-quality extracts and essential oils from Helichrysum italicum, as well as methods for determining their antioxidative, antimicrobial, anti-inflammatory, and anticarcinogenic activities. Finally, new ideas for in silico studies of molecular mechanisms of bioactive polyphenols from Helichrysum italicum, together with novel suggestions for their improved bioavailability through diverse encapsulation techniques, are introduced. Helichrysum italicum polyphenolic compounds biological effects extraction methods distillation methods encapsulation methods polifenoli biološki efekti ekstrakcija destilacija enkapsulacija true false true MDPI Angleški jezik Slovenski jezik https://www.mdpi.com/journal/foods Pregledno delo 2024-03-15 14:43:35 2024-03-15 15:01:57 2024-05-20 10:45:19 0000-00-00 00:00:00 2023 0 0 Str. 1-34 Št. 4, št. članka 802 Letn. 12 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2023-01-16 2023-02-11 2023-02-13 577 142205955 10.3390/foods12040802 2304-8158 Furlan-2023-_i_Helichrysum_italicum__i___From.pdf Furlan-2023-_i_Helichrysum_italicum__i___From.pdf 1 ABC7F697351A6B720433757F1E66A187 0efa2d2af793e1f3850ea798b0956637d98440b81f37bc6ab399c47d97c36044 60f17bc4-e2d4-11ee-9bc5-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=176915 https://www.mdpi.com/2304-8158/12/4/802 0 713a39c7-e2d4-11ee-9bc5-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=176916 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0