20.500.12556/DKUM-88276 Human threat circuits threats of pain, aggressive conspecific, and predator elicit distinct BOLD activations in the amygdala and hypothalamus Threat processing, enabled by threat circuits, is supported by a remarkably conserved neural architecture across mammals. Threatening stimuli relevant for most species include the threat of being attacked by a predator or an aggressive conspecific and the threat of pain. Extensive studies in rodents have associated the threats of pain, predator attack and aggressive conspecific attack with distinct neural circuits in subregions of the amygdala, the hypothalamus and the periaqueductal gray. Bearing in mind the considerable conservation of both the anatomy of these regions and defensive behaviors across mammalian species, we hypothesized that distinct brain activity corresponding to the threats of pain, predator attack and aggressive conspecific attack would also exist in human subcortical brain regions. human threat responses translational neuroscience threat conditioning threat types MRI threat circuit človeški odzivi na nevarnosti translacijska nevroznanost pogojevanje z nevarnostmi različne vrste nevarnosti funkcijski fMR možganska pot za obdelavo nevarnosti true true true Frontiers Research Foundation Angleški jezik Slovenski jezik Članek v reviji 2024-04-12 15:14:46 2024-04-12 15:32:43 2024-05-07 13:35:44 0000-00-00 00:00:00 2023 0 0 Str. 1-19 Letn. 13 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2022-10-06 2022-12-16 2023-01-09 159.96:616.89 137849347 10.3389/fpsyt.2022.1063238 1664-0640 Bertram-2023-Human_threat_circuits__Threats_of.pdf Bertram-2023-Human_threat_circuits__Threats_of.pdf 1 90AEC9268B3EA7EA26A0815066EC09BC 47569eeef5db7402ffb54fc2cb10bc6235f3ac549b654f784b314a9b4343c5fc ccb43483-f8d0-11ee-a0d6-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=178491 https://doi.org/10.3389/fpsyt.2022.1063238 0 b22fa4c8-f8ce-11ee-a0d6-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=178490 Filozofska fakulteta 0 0 0