20.500.12556/DKUM-88379 Kardiotoksičnost in več-organska odpoved zaradi zastrupitve z valproatom case report and review of the literature Cardiotoxicity and multiorgan system failure caused by valporate poisoning We report the case of severe valproate intoxication presenting as multiorgan failure. This is the first report to describe severe cardiac involvement, in which a 19-year-old woman developed atrial fibrillation, diffuse T wave inversion and QT c interval prolongation with elevated specific biochemical markers of myocardial damage. After 7 days of treatment, including supportive care, gas tric lavage, activated charcoal, mannitol and hemodialysis, the patient recovered completely . After the poisoning there were no patho- logical echocardiographic changes and one month after discharge exercise stress testing did not provoke ischemia or arrhythmias. kardiotoksičnost večorganska odpoved valproat cardiotoxicity multiorgan failure valproic acid true true false Angleški jezik Slovenski jezik Znanstveno delo 2024-04-19 08:53:12 2024-04-19 08:53:14 2024-04-20 03:28:37 0000-00-00 00:00:00 2009 0 0 str. 52-56 št. 2 Letn. 2 2009 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2009-01-01 615.9 26384345 1855-5640 07.pdf 07.pdf 1 96F19DDE59A9DABFFA9671D925592EF4 3ac127f2fd84ac80cc48ff64a32533b0410b0429024b4bf1bbc55d13dd1a57b8 b356d3c1-fe19-11ee-8dad-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=178739 Medicinska fakulteta Acta medico-biotechnica 0 0 0