20.500.12556/DKUM-88421 Electrodermal activity and heart rate variability for detection of peripheral abnormalities in type 2diabetes a review Modern medicine exhibits an upward trend towards non-invasive methods for early detection of disease and long-term monitoring of patients’ health. Diabetes mellitus and its complications are a promising area for implementation of new medical diagnostic devices. One of the most serious complications of diabetes is diabetic foot ulcer. The main causes responsible for diabetic foot ulcer are ischemia caused by peripheral artery disease and diabetic neuropathy caused by polyol pathway-induced oxidative stress. Autonomic neuropathy impairs function of sweat glands, which can be measured by electrodermal activity. On the other hand, autonomic neuropathy leads to changes in heart rate variability, which is used to assess autonomic regulation of the sinoatrial node. Both methods are enough sensitive to detect pathological changes caused by autonomic neuropathy and are promising screening methods for early diagnosis of diabetic neuropathy, which could prevent the onset of diabetic ulcer. diabetes mellitus diabetic foot ulcer autonomic neuropathy electrodermal activity heart rate variability diabetes mellitus diabetična razjeda stopala avtonomna nevropatija elektrodermalna aktivnost variabilnost srčnega utripa true false true Association of Basic Medical Sciences of FBIH Angleški jezik Slovenski jezik Znanstveno delo 2024-04-22 11:34:26 2024-04-22 11:40:15 2024-04-23 03:12:32 0000-00-00 00:00:00 2023 0 0 Str. 740-751 Št. 5 Letn. 23 2023 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2022-11-28 2023-02-12 2023-02-16 616 142478083 10.17305/bb.2022.8561 2831-0896 Znidaric-2023-Electrodermal_activity_and_heart.pdf Znidaric-2023-Electrodermal_activity_and_heart.pdf 1 271BE4D131928DDB5E0AF5F04A3BF086 f35f11ab331f5f9051e682d3582420f56e8e291c39bd81d6311fea466b06b40f 2caec639-008c-11ef-a521-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=178821 https://doi.org/10.17305/bb.2022.8561 0 37e967c2-008c-11ef-a521-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=178822 Medicinska fakulteta 0 0 0