20.500.12556/DKUM-89985 Hemodynamic response to high- and low-load resistance exercise in patients with coronary artery disease a randomized, crossover clinical trial Low-load resistance exercise (LL-RE) is recommended as an adjunct therapy to aerobic exercise during cardiac rehabilitation in patients with coronary artery disease. The safety and hemodynamic response to high-load (HL) RE remain unknown. The aim of this study was to evaluate the hemodynamic response during both HL-RE and LL-RE prior to cardiac rehabilitation. Forty-three patients with coronary artery disease and/or percutaneous coronary intervention performed three sets of leg-press exercise using HL-RE (eight repetitions at the intensity of 80% of one repetition maximum (1-RM)) and LL-RE (16 repetitions at the intensity of 40% 1-RM) in a randomized crossover sequence. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and rating of perceived exertion were measured at baseline, after each set of RE and post-exercise. No clinically relevant changes in HR and BP or in patient-reported symptoms were recorded during HL-RE or LL-RE. Compared with baseline, HR and SBP increased during LL-RE (from 66 bpm to 86 bpm, time effect: p < 0.001; from 129 mmHg to 146 mmHg, time effect: p < 0.001) and HL-RE (from 68 bpm to 86 bpm, time effect: p < 0.001; from 130 mmHg to 146 mmHg, time effect: p < 0.001). Compared with HL-RE, the increase in HR was greater after the final set of LL-RE (32% vs. 28%, p = 0.015), without significant differences in SBP and DBP between LL-RE and HL-RE. Rating of perceived exertion was higher after the 1st set of HL-RE compared with LL-RE (median (interquartile range): 6 (5–7) vs. 6 (5–6), p = 0.010). In patients with coronary artery disease, both HL-RE and LL-RE were safe and well-tolerated. Hemodynamic changes were similar and within the physiological response to RE. sport cardiac rehabilitation resistance training blood pressure heart rate šport srčno žilna rehabilitacija vztrajnostni trening krvni tlak srčni utrip true false true MDPI Angleški jezik Slovenski jezik Znanstveno delo 2024-08-20 14:14:06 2024-08-20 14:32:23 2024-08-21 03:41:19 0000-00-00 00:00:00 2021 0 0 Str. 1-12 Št. 8, št. članka 3905 Letn. 18 2021 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2021-03-08 2021-04-06 2021-04-08 616.1:796.01 59012611 10.3390/ijerph18083905 1660-4601 Kambic-2021-Hemodynamic_Response_to_High-_and.pdf Kambic-2021-Hemodynamic_Response_to_High-_and.pdf 1 C10F413E01E69427C51AC58ECFF5E928 f24b212d49d7e895c625559a08632a6549c21b24c38aa4f6e53735665acee95f 023aa6e2-5ef0-11ef-abdc-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=182764 https://doi.org/10.3390/ijerph18083905 0 b66b0046-5eed-11ef-abdc-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=182759 Fakulteta za naravoslovje in matematiko 0 0 0