20.500.12556/DKUM-90078 Izboljšanje lastnosti škrobnih aerogelov z dodatkom hitozana diplomsko delo visokošolskega strokovnega študijskega programa I. stopnje Enhancing starch aerogels through chitosan modification Namen diplomskega dela je bil sintetizirati polisaharidne aerogele na osnovi škroba z dodatkom hitozana ter preučiti vpliv dodatka hitozana na njihove termične in strukturne lastnosti. Polisaharidni aerogeli so izjemno lahki in porozni materiali, ki so se zaradi svoje biokompatibilnosti in biorazgradljivosti v zadnjem desetletju izkazali kot obetavni kandidati za razvoj novih metod v biomedicinskih aplikacijah. V eksperimentalnem delu smo s sol-gel sintezo pripravili škrobno-hitozanske aerogele pri različnih koncentracijah obeh polimerov, ki smo jih nato posušili s superkritičnim ogljikovim dioksidom. Sušenje smo izvedli pri 40 °C in 120 bar na polindustrijski napravi za superkritično sušenje UHDE. Lastnosti škrobno-hitozanskih aerogelov smo karakterizirali z metodami plinske adsorpcije, vrstične elektronske mikroskopije (SEM), Fourierjeve transformacijske infrardeče spektroskopije (FTIR), termogravimetrične analize (TGA) in diferencialne vrstične kalorimetrije (DSC). Nazadnje smo z izvedbo testov nabrekanja in stabilnosti preučili njihovo obnašanje v vodnem mediju. Rezultati so pokazali, da se je hitozan uspešno vgradil v strukturo škrobnih aerogelov ter izboljšal njihove strukturne in termične lastnosti. The aim of the thesis was to synthesize polysaccharide-based starch-chitosan aerogels and investigate the effects of chitosan addition on their thermal and structural properties. Polysaccharide aerogels are highly lightweight and porous materials, which, due to their biocompatible and biodegradable nature, have emerged as promising candidates for novel biomedical applications over the past decade. In the experimental section, starch-chitosan aerogels with varying concentrations of both polymers using sol-gel synthesis were prepared. The supercritical carbon dioxide drying followed. The drying process was conducted at 40 °C and 120 bar using a pilot-scale supercritical drying apparatus, UHDE. The structural and thermal properties of the starch-chitosan aerogels were characterized through gas adsorption, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC). Additionally, their behavior in aqueous media was assessed through swelling and stability tests. The results demonstrated that chitosan was successfully incorporated into the starch aerogel matrix, leading to enhanced structural and thermal properties. Aerogeli polisaharidi škrob hitozan superkritični fluidi sol-gel sinteza Aerogels polysaccharides starch chitosan supercritical fluids sol-gel synthesis true true false [R. Petrovič] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2024-08-22 11:19:47 2024-09-24 09:10:50 2025-01-10 03:09:21 0000-00-00 00:00:00 2024 0 Maribor 0 Maribor 1 spletni vir (1 datoteka PDF (VIII, 31 f.)) 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 66.091.3:544.774.2(043.2) 221572611 VS_Petrovic_Rok_2024.pdf VS_Petrovic_Rok_2024.pdf 1 1C746B83BD3769534F4BDB709A9E859F b38fa21c397ded2968796115677f49ffc18a4c6ffc863778782127244ac9ed50 36c5a5a6-6aa8-11ef-b7ab-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=184352 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0