20.500.12556/DKUM-90330 Probiotiki in migrene Probiotics and migraines Uvod: Migrena je pogosta nevrološka bolezen. Obstaja dvosmerna povezava med črevesjem in možgani preko črevesne mikrobiote. Črevesno mikrobioto lahko manipuliramo z vnosom probiotikov, s katerimi želimo načrtno izboljšati zdravje. Namen diplomskega dela je bil raziskati vpliv uživanja probiotikov pri pacientih z migreno na pojavnost migren in bolečino. Metode: Izvedli smo pregled literature, pridobljene iz podatkovnih baz: CINAHL Ultimate, Cochrane Library, PubMed, ScienceDirect in Sage Journals. S PRISMA diagramom smo predstavili potek pregleda in izbrane raziskave razvrstili po hierarhiji dokazov. Za analizo in sintezo podatkov smo uporabili vsebinsko analizo. Rezultati: Raziskave so pokazale, da so probiotiki lahko koristni pri zmanjševanju frekvence in intenzitete migren. Za najbolj koristne so se izkazali probiotiki iz rodov laktobacilov in bifidobakterij. Razprava in zaključek: Probiotiki imajo pozitiven vpliv na nevrogene bolezni, saj zmanjšujejo učinek oksidativnega stresa. Tako zmanjšujejo pojavnost in bolečino migren, zato bi bilo smiselno uvesti probiotike kot podporno zdravljenje migren. Introduction: Migraine is a common neurological disease. There is a two-way connection between the gut and the brain via the gut microbiota. Intestinal microbiota can be manipulated by taking probiotics, with which we want to improve health in a planned way. The aim of the thesis was to investigate the impact of probiotic consumption in patients with migraine on the occurrence of migraines and pain. Methods: We performed a literature review obtained from the following databases: CINAHL Ultimate, Cochrane Library, PubMed, Science Direct and Sage Journals. The PRISMA diagram was used to present the process of the review and to classify the selected research according to the hierarchy of evidence. Content analysis was used to analyse and synthesize the data. Results: Research has shown that probiotics may be helpful in reducing the frequency and intensity of migraines. Probiotics from the lactobacilli and bifidobacteria genera proved to be the most beneficial. Discussion and conclusion: Probiotics have a positive effect on neurogenic diseases, as they reduce the effect of oxidative stress. Thus, they reduce the incidence and pain of migraines, so it would be reasonable to introduce probiotics as a supportive treatment for migraines. probiotiki migrene bolečina probiotics migraines pain true true false [A. Peserl] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2024-08-29 15:53:44 2024-12-09 18:13:14 2025-02-18 14:52:35 0000-00-00 00:00:00 2024 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 613.292+616.857(043.2) 215621891 VS_Peserl_Ana_2024.pdf VS_Peserl_Ana_2024.pdf 1 13B90BE833E1C05E213FB54E574FFB5A eb4e3488f7f3bb5e5c70f8fddea49354689dd001b903bf0c2ed68e142ad5a8ae 797a0bd3-8f14-11ef-97e7-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=186692 Fakulteta za zdravstvene vede 0 0 0