20.500.12556/DKUM-90674 Supercritical fluid extraction of cannabinoids and their analysis by liquid chromatography and supercritical fluid chromatography a short review Extraction of cannabinoids from different parts of the plant matrix is often carried out by various traditional methods based on the use of organic solvents. Supercritical fluid extraction (SFE) has emerged as one of the most intriguing approaches for the extraction of cannabinoids. This review examines the importance of the SFE of cannabinoids, extraction parameters, selection of a suitable co-solvent/modifier, and appropriate sample preparation. To characterise the composition of the mixture of cannabinoids different analysis methods can be applied. One of them is high-performance liquid chromatography (HPLC), which requires no derivatisation of the analysed sample and allows for a determination of a wide variety of both acidic and neutral cannabinoids. Nevertheless, liquid chromatography with tandem mass spectrometry (LC-MS/MS) is gaining increasing importance due to its superior identification of analytes which is based on both the retention times of analytes as well as specific qualifier ions. Another interesting analytical method is supercritical fluid chromatography (SFC), which uses supercritical fluids (SCFs) such as CO2 in combination with different modifiers, to successfully separate and determine cannabinoids. The use of SFC allows for an efficient and above all, rapid separation of the desired analytes. There is an essential need to efficiently investigate the influence of various experimental parameters on the retention behaviour of cannabinoids in SFC. supercritical fluid extraction supercritical CO2 liquid chromatography with tandem mass spectrometry supercritical fluid chromatography superkritična ekstrakcija tekočin kromatografioja tekočin superkritični ogljikov dioksid masna spektrometrija true false true Elsevier Angleški jezik Slovenski jezik https://www.sciencedirect.com/journal/journal-of-co2-utilization © 2024 The Authors Znanstveno delo 2024-09-14 03:28:05 2024-12-10 08:56:13 2026-02-13 13:55:56 0000-00-00 00:00:00 2024 0 0 13 str. Vol. 86, [article no.] 102907 Aug. 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2024-03-08 2024-08-13 2024-08-21 66.02 207374083 10.1016/j.jcou.2024.102907 2212-9839 1-s2.0-S2212982024002427-main.pdf 1-s2.0-S2212982024002427-main.pdf 1 EFB4F103CEBDD64F5F0FC509E24108E9 1dfec6bfae230d75135987a0e3b8f87f688ec0821b2096a9ee0aa5371cdf64e2 dc5c1625-b6cc-11ef-9a40-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=187220 https://www.sciencedirect.com/science/article/pii/S2212982024002427?via%3Dihub 0 e76ef8e6-b6cc-11ef-9a40-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=187221 https://doi.org/10.1016/j.jcou.2024.102907 0 55de8995-08db-11f1-8973-00155d00019a https://dk.um.si/Dokument.php?lang=slv&id=203334 Fakulteta za kemijo in kemijsko tehnologijo 0 0 0