20.500.12556/DKUM-91123 Antimicrobial activity of amino-modified cellulose nanofibrils decorated with silver nanoparticles Silver nanoparticles (Ag NPs) conjugated with amino-functionalized cellulose nanofibrils (NH2−CNFs) were in situ-prepared by reducing silver ions with free amino groups from NH2−CNFs. The spectroscopy and transmission electron microscopy measurements confirmed the presence of non-agglomerated nanometer-in-size Ag NPs within micrometer-large NH2−CNFs of high (20 wt.-%) content. Although the consumption of amino groups during the formation of Ag NPs lowers the ζ-potential and surface charge of prepared inorganic–organic hybrids (from +31.3 to +19.9 mV and from 2.4 to 1.0 mmol/g at pH 7, respectively), their values are sufficiently positive to ensure electrostatic interaction with negatively charged cell walls of pathogens in acidic and slightly (up to pH ~8.5) alkaline solutions. The antimicrobial activity of hybrid microparticles against various pathogens (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans) is comparable with pristine NH2−CNFs. However, a long-timescale use of hybrids ensures the slow and controlled release of Ag+ ions to surrounding media (less than 1.0 wt.-% for one month). amino-modified cellulose nanofibrils silver nanoparticles hybrid microparticles zeta-potential antimicrobial activity amino-modificirane celulozne nanofibrile nanodelci srebra hibridni mikrodelci zeta-potencial protimikrobno delovanje true false true MDPI Angleški jezik Slovenski jezik https://www.mdpi.com/journal/jfb © 2024 by the authors Članek v reviji 2024-11-08 03:07:37 2024-12-09 12:37:19 2026-01-15 03:10:11 0000-00-00 00:00:00 2024 0 0 14 str. iss. 10, [article no.] 304 Vol. 14 October 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2024-09-18 2024-10-11 2024-10-13 543.2/.9:620.3 214017539 10.3390/jfb15100304 2079-4983 jfb-15-00304.pdf jfb-15-00304.pdf 1 E9B843626315514CF845261AE9BD83B9 81f4fb822ff77d2c138f7a843df79dd48549167e82b5e17dd2c41b125693e094 05938405-f14e-11f0-8a93-00155d580e02 https://dk.um.si/Dokument.php?lang=slv&id=202015 https://www.mdpi.com/2079-4983/15/10/304 0 491a9e53-ad8d-11ef-88e2-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=187003 Fakulteta za strojništvo 0 0 0