20.500.12556/DKUM-91256 A method for the immobilization of chitosan onto urinary catheters A method for the immobilization of an antibacterial chitosan coating to polymeric urinary medical catheters is presented. The method comprises a two-step plasma-treatment procedure, followed by the deposition of chitosan from the water solution. In the first plasma step, the urinary catheter is treated with vacuum-ultraviolet radiation to break bonds in the polymer surface film and create dangling bonds, which are occupied by hydrogen atoms. In the second plasma step, polymeric catheters are treated with atomic oxygen to form oxygen-containing surface functional groups acting as binding sites for chitosan. The presence of oxygen functional groups also causes a transformation of the hydrophobic polymer surface to hydrophilic, thus enabling uniform wetting and improved adsorption of the chitosan coating. The wettability was measured by the sessile-drop method, while the surface composition and structure were measured by X-ray photoelectron spectroscopy and Fourier-transform infrared spectroscopy. Non-treated samples did not exhibit successful chitosan immobilization. The effect of plasma treatment on immobilization was explained by noncovalent interactions such as electrostatic interactions and hydrogen bonds. polymer chitosan immobilization adhesion plasma-surface modification biopolymers polimeri imobilizacija hitozana adhezija površinska modifikacija plazemska funkcionalizacija biopolimeri true false true MDPI Angleški jezik Slovenski jezik Znanstveno delo 2024-12-05 08:28:30 2024-12-05 08:53:45 2024-12-06 03:20:51 0000-00-00 00:00:00 2022 0 0 Str. 1-18 št. 23, št. članka 15075 Letn. 23 Dec. 2022 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2022-11-07 2022-11-28 2022-12-01 533 131927043 10.3390/ijms232315075 1422-0067 Vesel_2022_A_Method_for_the_Immobilization.pdf Vesel_2022_A_Method_for_the_Immobilization.pdf 1 63FCDB675AB857009F6A00B509C41DB2 b79600b886a1c8d846e5b3ab386091f7b263e37d64d933bf1e34e3384a3a0d94 a613ad4f-b2dd-11ef-9aff-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=187098 https://doi.org/10.3390/ijms232315075 0 b3ae4731-b2dd-11ef-9aff-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=187099 Fakulteta za strojništvo 0 0 0