20.500.12556/DKUM-91363 Simulation study of different OPM-MEG measurement components Magnetoencephalography (MEG) is a neuroimaging technique that measures the magnetic fields of the brain outside of the head. In the past, the most suitable magnetometer for MEG was the superconducting quantum interference device (SQUID), but in recent years, a new type has also been used, the optically pumped magnetometer (OPM). OPMs can be configured to measure multiple directions of magnetic field simultaneously. This work explored whether combining multiple directions of the magnetic field lowers the source localization error of brain sources under various conditions of noise. We simulated dipolar-like sources for multiple configurations of both SQUID- and OPM-MEG systems. To test the performance of a given layout, we calculated the average signal-to-noise ratio and the root mean square of the simulated magnetic field; furthermore, we evaluated the performance of the dipole fit. The results showed that the field direction normal to the scalp yields a higher signal-to-noise ratio and that ambient noise has a much lower impact on its localization error; therefore, this is the optimal choice for source localization when only one direction of magnetic field can be measured. For a low number of OPMs, combining multiple field directions greatly improves the source localization results. Lastly, we showed that MEG sensors that can be placed closer to the brain are more suitable for localizing deeper sources. magnetoencephalography optically pumped magnetometers superconducting quantum interference device volume conductor boundary element method equivalent current dipole source localization ambient noise spontaneous brain noise magnetoencefalografija optično črpani magnetometri superprevodna kvantna interferenčna naprava volumski prevodnik metoda mejnih elementov ekvivalentni tokovni dipol lokalizacija vira šum okolja spontani možganski šum true false true MDPI Angleški jezik Slovenski jezik Znanstveno delo 2024-12-16 12:03:22 2024-12-16 12:16:05 2024-12-17 03:11:09 0000-00-00 00:00:00 2022 0 0 Str. 1-16 št. 9, št. članka 3184 Letn. 22 Apr. 2022 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2022-03-16 2022-04-20 2022-04-21 537:616.8 106551555 10.3390/s22093184 1424-8220 Marhl_2022_Simulation_Study_of_Different.pdf Marhl_2022_Simulation_Study_of_Different.pdf 1 8422FAAA1D3FACE881934D6C0141DAE9 71f7c873b0ede34e61ed3a117456d5ceaa5d3431e024a577b74b88f586cac78c f99ca4fb-bb9e-11ef-8250-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=187376 https://doi.org/10.3390/s22093184 0 5e5a8062-bb9d-11ef-8250-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=187375 Fakulteta za naravoslovje in matematiko 0 0 0