20.500.12556/DKUM-92204 Total Knee replacement with an uncemented porous tantalum tibia component: A failure analysis Porous tantalum has been extensively used in orthopaedic surgery, including uncemented total knee arthroplasty (TKA). Favourable results were reported with earlier monobloc tibial components and the design evolved to modular implants. We aimed to analyse possible causes for extensive medial tibia bone loss, resulting in modular porous tantalum tibia baseplate fracture after primary TKA. Retrieved tissue samples were scanned with 3 MeV focused proton beam for Proton-Induced X-ray Emission (micro-PIXE) elemental analysis. Fractographic and microstructural analysis were performed by stereomicroscopy. A full 3D finite-element model was made for numerical analysis of stress–strain conditions of the tibial baseplate. Histological examination of tissue underneath the broken part of the tibial baseplate revealed dark-stained metal debris, which was confirmed by micro-PIXE to consist of tantalum and titanium. Fractographic analysis and tensile testing showed that the failure of the tibial baseplate fulfilled the criteria of a typical fatigue fracture. Microstructural analysis of the contact surface revealed signs of bone ingrowth in 22.5% of the surface only and was even less pronounced in the medial half of the tibial baseplate. Further studies are needed to confirm the responsibility of metal debris for an increased bone absorption leading to catastrophic tibial tray failure. total knee arthroplasty uncemented cementless trabecular metal porous tantalum tibial component cementless baseplate fracture totalna kolenska endoproteza brez cementa trabekularna kovina porozni tantal tibialna komponenta zlom temeljne plošče brez cementa true false true MDPI AG Angleški jezik Slovenski jezik https://www.mdpi.com/journal/materials © 2022 by the authors Članek v reviji 2025-03-20 13:15:22 2025-03-20 13:15:22 2025-03-21 03:10:50 0000-00-00 00:00:00 2022 0 0 13 str. iss. 7 (2575) Vol. 15 Mar. 2022 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2022-02-20 2022-03-30 2022-03-31 620.18:615.461 103785475 10.3390/ma15072575 1996-1944 materials-15-02575-v3.pdf materials-15-02575-v3.pdf 1 1E272BDFA17161C4D4569FC6770266F0 15f654bd7e9e116ea196ea4574979741ffe785eff5e247019e63e6047307aa52 728dee3b-0585-11f0-9be3-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=189520 https://www.mdpi.com/1996-1944/15/7/2575 0 783c3afb-0585-11f0-9be3-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=189521 Fakulteta za strojništvo 0 0 0