20.500.12556/DKUM-92636 Stopnja umrljivosti po transkatetrski zamenjavi aorte zaklopke v primerjavi s kirurško zamenjavo aorte zaklopke Mortality rate after transcatheter aortic valve replacement compared with surgical aortic valve replacement Uvod: Aortna stenoza (AS) je najpogostejši vzrok srčnega popuščanja v razvitih državah. Incidenca aortne stenoze s starostjo narašča in prizadene približno 10 % prebivalstva. Tradicionalno se AS zdravi s kirurško zamenjavo aortne zaklopke (SAVR), v zadnjih časih pa se vse več uporablja transkatetrska zamenjava aortne zaklopke (TAVR). Metode: V zaključnem delu smo sistematično pregledali in analizirali znanstveno literaturo. Literaturo smo iskali v mednarodnih podatkovnih bazah PubMed, CINAHL Ultimate in ScienceDirect. Postopek iskanja literature smo prikazali s PRISMA-diagramom, rezultate smo prikazali z evalvacijsko in s sintezno tabelo. Rezultati: V končno analizo smo vključili 15 raziskav. Rezultati so pokazali manjšo stopnjo umrljivosti po TAVR in višjo po SAVR. Slabosti SAVR posega so večje krvavitve, na novo nastala atrijska fibrilacija in akutne poškodbe ledvic. Slabosti TAVR so potreba po vsaditvi trajnega srčnega spodbujevalnika, aortna regurgitacija in žilni zapleti. Razprava in zaključek: Za odločitev TAVR ali SAVR-poseg je potrebna celovita klinična ocena pacienta in sodelovanje kardiološkega tima za optimalno izveden poseg, ki omogoči pacientu kvalitetno življenje. Z napredkom tehnologije bo TAVR predstavljal večkrat izbrano alternativo SAVR-posegu. Abstract Introduction: Aortic stenosis (AS) is the most common cause of heart failure in the developed world. The incidence of AS increases with age and affects approximately 10% of the population. Traditionally, AS has been treated by surgical aortic valve replacement (SAVR), but more recently transcatheter aortic valve replacement (TAVR) has been increasingly used. Methods: The literature was searched using the international databases PubMed, CINAHL Ultimate and ScienceDirect. A PRISMA diagram was used to present the literature search process, and the results were presented in an appraisal and synthesis table. Results: The results showed a lower mortality rate after TAVR and a higher mortality rate after SAVR. The disadvantages of SAVR are major bleeding, new-onset atrial fibrillation, and acute kidney injury. The disadvantages of TAVR are the need for permanent pacemaker implantation, aortic regurgitation, and vascular complications. Discussion and conclusion: The decision to perform TAVR or SAVR requires a comprehensive clinical assessment of the patient and collaboration with the cardiology team to optimise the procedure to provide a good quality of life for the patient. As technology advances, TAVR will become the alternative of choice to SAVR. aortna stenoza TAVR SAVR stopnja umrljivosti aortic stenosis TAVR SAVR mortality rate true true false [L. Bračko] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2025-04-25 20:58:35 2025-08-20 11:23:32 2025-08-21 03:09:42 0000-00-00 00:00:00 2025 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.132-089+616-036.8(043.2) 241132803 VS_Bracko_Lucijan_2025.pdf VS_Bracko_Lucijan_2025.pdf 1 078B7BF715A0DB602B0C8F31E1554E69 241d7438a9eb19aec2fa2a16a7fd5dfde25ce748689ee67290b0065732e3d04a 41693ed8-7da7-11f0-a14c-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=195692 Fakulteta za zdravstvene vede 0 0 0