20.500.12556/DKUM-93909 Komorbidnost shizofrenije in odvisnosti od opioidov pri odraslih Comorbidity of schizophrenia and addiction in adults Uvod: Duševno zdravje je v današnjem času zelo pomembno, saj se vedno pogosteje pojavljajo duševne motnje, ki pomembno vplivajo na naše vsakodnevno življenje. Med duševne motnje sodita tudi shizofrenija in odvisnost od opioidov, ki pa sta velikokrat komorbidna in lahko imata velik vpliv na pacienta. Namen zaključnega dela je bil raziskati, kako je pojavnost shizofrenije pri odraslih povezana s komorbidnostjo odvisnosti od opioidov. Metode: Izveden je bil pregled literature v podatkovnih bazah: PubMed, CINAHL Ultimate in Web of Science s ključnimi besedami: shizofrenija, odvisnost, opioidi, komorbidnost in odrasli, v obdobju od 2015 do 2025. Izvedena je bila narativna analiza virov, zajetih v pregled literature. Rezultati: Od 138 raziskav je bilo v končno analizo vključenih sedem raziskav. Ugotovljeno je bilo, da je komorbidnost zelo pogosta, povezana pa je z različnimi dejavniki, med katerimi izstopajo demografski dejavniki, kot sta spol in starost. Razprava in zaključek: Komorbidnost med shizofrenijo in odvisnostjo od opioidov je pri odraslih prisotna, vendar v izvedenem pregledu literature ni bilo dokazov, da je odvisnost od opioidov povezana oz. vpliva na nastanek shizofrenije ali obratno. Za nadaljnje raziskovanje tega področja o vzročnih povezavah med odvisnostjo od opioidov in shizofrenije se priporočajo bolj poglobljene metode in strategije pregleda literature. Introduction: Mental health is very important today, as mental disorders that significantly affect our daily lives are becoming increasingly common. Mental disorders include schizophrenia and opioid dependence, which are often comorbid and can have a major impact on patients. The aim of this thesis was to investigate how the prevalence of schizophrenia in adults is related to the comorbidity of opioid dependence. Methods: A literature review was conducted in the PubMed, CINAHL Ultimate and Web of Science databases using the keywords: schizophrenia, opioid addiction, comorbidity and adults, covering the period from 2015 to 2025. A narrative analysis of the sources included in the literature review was performed. Results: Of the 138 studies, seven were included in the final analysis. It has been found that comorbidity is very common and is associated with various factors, among which demographic factors such as gender and age stand out. Discussion and conclusion: Comorbidity between schizophrenia and opioid dependence is present in adults, but a review of the literature found no evidence that opioid addiction is associated with or influences the development of schizophrenia, or vice versa. For further exploration of this area of causal links between opioid dependence and schizophrenia, more in-depth methods and strategies for reviewing the literature are recommended. Duševno zdravje razširjenost opiati psihoza odrasli Mental health prevalence opiates psychosis adults true true false [A. Grah] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2025-07-25 10:37:42 2025-10-24 13:46:45 2025-12-19 15:47:30 0000-00-00 00:00:00 2025 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-06:616.895.8+343.976-053.8(043.2) 252346115 VS_Grah_Aljosa_2025.pdf VS_Grah_Aljosa_2025.pdf 1 85D39F9944BEFBEFCA8F12EE1993C9C2 3765bb397ebc5c33fb0d7b06572522b47eaeb8ed14f9f5e44003a51ed8b73564 9a5d14ec-9180-11f0-b621-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=198366 Fakulteta za zdravstvene vede 0 0 0