20.500.12556/DKUM-94062 Beneficial effects of castanea sativa wood extract on the human body and possible food and pharmaceutical applications The aim of this review was to investigate the potential use of Castanea sativa wood extract as a food supplement and to evaluate its beneficial properties for human health. The results of the limited amount of studies suggest promising properties, including potential anti-inflammatory effects. The literature indicates that the extract, which is rich in bioactive compounds such as tannins, offers promising therapeutic possibilities for the treatment of conditions associated with chronic inflammation. Consequently, interest in its use in food and pharmaceuticals is growing. Phytochemical studies have reported antioxidant and antimicrobial activities, and anti-inflammatory, anticancer, hypolipidemic, hypoglycemic, and neuroprotective activities. A suitable extraction method and solvent is crucial for the isolation of bioactive compounds, being green extraction technologies outstanding for the industrial recovery of chestnut wood’s bioactive compounds. Nevertheless, it is important to emphasize the importance of adhering to regulatory guidelines and obtaining the necessary approvals from regulatory authorities to ensure product safety and compliance. The regulation of herbal medicinal products with proven efficacy and traditional herbal medicinal products is well defined, monitored by authorized bodies, and subject to strict control measures. It is noteworthy that medicinal products are subject to stringent quality testing to ensure safety and efficacy in use, whereas there are no comparable regulatory standards and specific labeling requirements for dietary supplements. When using herbal products, compliance with established standards in health research is essential. Castanea sativa wood extracts tannins antioxidat activity anti-inflammatory activity antimicrobial activity kostanj lesni ekstrakti antioksidacijske lastnosti antimikrobne lastnosti protivnetne lastnosti true false true MDPI Angleški jezik Slovenski jezik https://www.mdpi.com/journal/plants © 2024 by the authors Članek v reviji 2025-07-30 10:08:04 2025-07-30 10:08:05 2025-07-31 03:13:31 0000-00-00 00:00:00 2024 0 0 18 str. iss. 7, [article no.] 914 Vol. 13 March 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2024-02-19 2024-03-09 2024-03-22 66.02 190838275 10.3390/plants13070914 2223-7747 plants-13-00914.pdf plants-13-00914.pdf 1 82402F6AC213D02C1AACB623D031767E 37c0191878332af979b30491c2214210d48b17d17b7d3761aaece5df4a93f181 dacdaba2-6d1c-11f0-b54a-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=194517 https://www.mdpi.com/2223-7747/13/7/914 0 e135fea9-6d1c-11f0-b54a-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=194518 Fakulteta za kemijo in kemijsko tehnologijo Medicinska fakulteta Pravna fakulteta 0 0 0