20.500.12556/DKUM-94580 Numerična simulacija dinamične termografije diplomsko delo Numerical simulation of dynamic thermography V diplomskem delu je obravnavana numerična simulacija dinamične termografije. Termografija je brezkontaktna in neinvazivna tehnika za merjenje temperature. Obravnavali smo prenos toplote med tumorjem in okoliškim tkivom, ki temelji na Pennesovem numeričnem modelu, kateremu sta dodana toplotni izvor in ponor zaradi perfuzijskega pretoka in metabolizma. Za modeliranje temperaturne odvisnosti metabolizma in perfuzijskega pretoka smo uporabili van’t Hoffov efekt. Cilj diplomske naloge je dokazati prednosti dinamične termografije pred statično in določiti temperaturno odvisnost perfuzijskega pretoka in metabolizma celic. V prvem delu diplomske naloge je prikazana razlika med konstantnimi vrednostmi in termoregulacijskim modelom. Ugotovili smo, da pri termoregulacijskem modelu z vrednostjo koeficienta 1,1, dosegamo nižje temperaturne razlike na površini kože kot pri konstantnih vrednostih metabolizma in perfuzijskega pretoka. V nadaljevanju smo primerjali vpliv različnih vrednosti koeficientov perfuzijskega pretoka in metabolizma. Ugotovili smo tudi, da pri dinamični termografiji dosegamo višje temperaturne razlike na površini kože kot pri statični. Na koncu smo obravnavali vpliv časa in temperature hlajenja, ugotovili smo, da se temperaturna razlika med tumorjem in okoliškim tkivom povečuje z nižanjem temperature ohlajanja in večanjem časa podhladitve. The thesis discusses the numerical simulation of dynamic thermography. Thermography is a non-contact and non-invasive technique for measuring temperature. We studied heat transfer between a tumor and the surrounding tissue, based on Pennes’ numerical model, to which a heat source and sink due to perfusion flow and metabolism were added. To model the temperature dependence of metabolism and perfusion flow, we used the van’t Hoff effect. The aim of the thesis is to demonstrate the advantages of dynamic thermography over static thermography and to determine the temperature dependence of cellular metabolism and perfusion flow. In the first part of the thesis, the difference between constant values and the thermoregulatory model is presented. We found that, with a thermoregulatory model using a coefficient value of 1.1, we observe lower temperature differences on the skin surface compared to constant values of metabolism and perfusion flow. Subsequently, we compared the influence of different coefficient values for perfusion flow and metabolism. We also found that dynamic thermography yields higher temperature differences on the skin surface than static thermography. Finally, we examined the impact of cooling time and temperature. We found that the temperature difference between the tumor and surrounding tissue increases with lower cooling temperatures and longer cooling durations. termografija perfuzijski pretok krvi termoregulacija numerična simulacija termoregulacijski model tumor thermography perfusion blood flow thermoregulation numerical simulation thermoreguation model tumour true true false [B. Sarjaš] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2025-08-21 17:23:14 2025-10-02 15:55:26 2025-10-25 03:25:10 0000-00-00 00:00:00 2025 0 Maribor 0 Maribor 1 spletni vir (1 datoteka PDF (VII, 40 f.)) 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 519.6:772.96(043.2) 254664195 UN_Sarjas_Blaz_2025_nova.pdf UN_Sarjas_Blaz_2025_nova.pdf 1 8C3CC323118BC8B35A8CC34B80506AAE 35e7dcb31543d685dfcfaf67aae95dc4353a166c8c71516de298d348f1a4d8ce 62b2597e-9f97-11f0-9873-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=199543 Fakulteta za strojništvo 0 0 0