20.500.12556/DKUM-95059 Uporaba probiotikov pri zdravljenju otrok z drisko ob jemanju antibiotikov The use of probiotics in the treatment of children with antibiotic-associated diarrhea Uvod: Probiotiki predstavljajo pomembne mikroorganizme, ki imajo pozitivne učinke pri gostiteljih, kadar jih ti zaužijejo ali kako drugače aplicirajo v ustreznih količinah. S pregledom literature smo želeli raziskati učinkovitost probiotika na zdravljenje ali zmanjšanje pojavnosti driske pri otrocih, ki jo povzroči jemanja antibiotika. Metode: Izvedli smo pregled, analizo in sintezo literature. Iskanje je potekalo po podatkovnih bazah PubMed, ScienceDirect, Wiley, CINAHL. S pomočjo diagrama PRISMA smo prikazali potek iskanja. Rezultati: V končno analizo smo vključili 17 raziskav. Ugotovitve raziskav se razlikujejo glede na sev probiotika, ki je bil raziskan. Pri večini je prišlo do zmanjšanja pogostosti in trajanja driske, lajšanja neugodnih trebušnih simptomov, manj zapletov in zmanjšanje števila hospitalizacij pri otrocih, ki imajo drisko, zaradi jemanja antibiotika. Razprava in Zaključek: Ugotovili smo, da imajo določeni probiotiki pozitiven učinek pri otrocih z drisko, ki jo povzroči jemanja antibiotikov. Menimo, da je na tem področju smiselno nadaljnje raziskovanje zlasti probiotičnih sevov, ki še niso dobro raziskani ali pa zgolj ugotavljanje ustrezne doze ali trajanja apliciranja probiotika za polno učinkovitost, pri že raziskanih sevih, saj so driske zaradi jemanja antibiotikov pri otrocih pogoste in vplivajo na potek zdravljenja in hkrati tudi na adherenco staršev. Še bolj učinkovito raziskani probiotiki, bi zdravstvenim delavcem bistveno olajšali oskrbo in svetovanje ob driski, ki se pojavi zaradi jemanja antibiotika pri otrocih. Introduction: Probiotics represent important microorganisms that have positive effects on hosts when administered in appropriate amounts. By conducting a literature review, we aimed to examine the efficacy of probiotics in the treatment and prevention of antibiotic-associated diarrhea in children. Methods: We conducted a review, analysis and synthesis of literature. For the search we used the following databeses PuBMed, ScienceDirect, Wiley, CINAHL. We depicted the progress of the search using the PRISMA flow diagram. Results: We included 17 studies in the final study. The findings of the studies vary depending on the specific probiotic strain invesigated. In the majority of cases, a reduction in the frequency and duration of diarrhea was observed, along with alleviation of abdominal discomfort, fewer complications, and a decreased rate of hospitalization among children experiencing antibiotic-associated diarrhea. Discussion and conclusion: Our findings indicate that certain probiotic benefit children with antibiotic-associated diarrhea. Further research in this area is warranted, especially on less-studied strains and on optimizing the dosage and duration of adminisration for thosewith proven efficacy., beceause antibiotic-associated diarrhea is common in children, affecting treatment and parental adherence.Well-studied probiotics could significantly support healthcare professionals in its management. probiotik otroci driska antibiotik probiotic child diarrhea antibiotic true true false [U. Bratušek] Slovenski jezik Angleški jezik Magistrsko delo/naloga 2025-09-03 09:57:05 2025-11-18 14:06:03 2026-02-04 14:51:37 0000-00-00 00:00:00 2025 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.34-008.314.4-053.5:613.292:615.33(043.2) 256373251 MAG_Bratusek_Urska_2025.pdf MAG_Bratusek_Urska_2025.pdf 1 C0E545B00479FFA5F88861C686E4160F bad5a36c459ef33e286252dc5c59dde785a57d239c6f479572f05f53064a29b4 36fa7cff-889d-11f0-82a8-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=197434 Fakulteta za zdravstvene vede 0 0 0