20.500.12556/DKUM-95731 Primerjava plinske analize arterijske in periferne venske krvi pri bolnikih z akutno dihalno odpovedjo in COVIDOM-19 Comparison of arterial and peripheral venous blood gas analysis in patients with acute respiratory failure and COVID-19 Uvod: Plinska analiza arterijske krvi je standardna metoda za oceno dihalne funkcije, vendar je invazivna in za bolnike neprijetna. Alternativa je plinska analiza periferne venske krvi, ki je manj boleča in enostavneje izvedljiva. Namen zaključnega dela je bil primerjati rezultate obeh metod pri bolnikih z akutno respiratorno odpovedjo in COVIDOM-19. Metode: Retrospektivno smo analizirali podatke 148 nešokiranih bolnikov. Opravili smo arterijsko in vensko plinsko analizo ter merili saturacijo s pulzno oksimetrijo. Za statistično obdelavo smo uporabili korelacijske teste in Bland-Altmanovo metodo za oceno ujemanja med metodami. Rezultati: Rezultati so pokazali visoko korelacijo med arterijsko in vensko analizo za pH (rs = 0,85), pCO₂ (rs = 0,76) in HCO₃ (rs = 0,85). Ti parametri so se izkazali za primerljive. Pri pO₂ in SO₂ so bile razlike bistveno večje, kar kaže, da venska analiza sama po sebi ni primerna za zanesljivo oceno oksigenacije krvi. Razprava in zaključek: Venska plinska analiza je uporabna za oceno pH, pCO₂ in HCO₃, ne pa tudi za oksigenacijo. V kombinaciji s pulzno oksimetrijo bi lahko zmanjšala potrebo po arterijskih punkcijah pri nešokiranih bolnikih. Introduction: Arterial blood gas analysis is the standard method for assessing respiratory function, but it is invasive and uncomfortable for patients. An alternative is peripheral venous blood gas analysis, which is less painful and easier to perform. This thesis aimed to compare the results of both methods in patients with acute respiratory failure and COVID-19. Methods: We retrospectively analysed data from 148 non-shocked patients. We performed arterial and venous gas analysis and measured saturation with pulse oximetry. For statistical processing, we used correlation tests and the Bland-Altman method to assess the agreement between the methods. Results: The results showed a high correlation between arterial and venous analysis for pH (rs = 0.85), pCO₂ (rs = 0.76), and HCO₃ (rs = 0.85). These parameters proved to be comparable. For pO₂ and SO₂, the differences were significantly greater, indicating that venous analysis alone is not suitable for reliable assessment of blood oxygenation. Discussion and Conclusion: Venous gas analysis is useful for assessing pH, pCO₂, and HCO₃, but not for oxygenation. Combined with pulse oximetry, it could reduce the need for arterial punctures in non-shocked patients. plinska analiza arterijske krvi plinska analiza periferne venske krvi akutna respiratorna odpoved COVID-19 oksigenacija krvi arterial blood gas analysis peripheral venous blood gas analysis acute respiratory failure COVID-19 blood oxygenation true true false [A. Ladinik] Slovenski jezik Angleški jezik Magistrsko delo/naloga 2025-10-16 13:16:22 2025-12-16 10:36:41 2026-02-04 15:30:08 0000-00-00 00:00:00 2025 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 612.15-056.24:616.24-008.4:578.834(043.2) 258719747 MAG_Ladinik_Aljaz_2025.pdf MAG_Ladinik_Aljaz_2025.pdf 1 6CE8E1DC90BC795E5B9625EF9DF4BB2C 443106bbac3f5d98a1aa20a3ff59df51a07a900388b93248560c7bd62d25502b d04f8447-b321-11f0-a3bd-00155d000105 https://dk.um.si/Dokument.php?lang=slv&id=200209 Fakulteta za zdravstvene vede 0 0 0