20.500.12556/DKUM-96766 A simplified longitudinal model for the development of Type 2 Diabetes Mellitus Obesity and diabetes are a progressively more and more deleterious hallmark of modern, well fed societies. In order to study the potential impact of strategies designed to obviate the pathological consequences of detrimental lifestyles, a model for the development of Type 2 diabetes geared towards large population simulations would be useful. The present work introduces such a model, representing in simplified fashion the interplay between average glycemia, average insulinemia and functional beta-cell mass, and incorporating the effects of excess food intake or, conversely, of physical activity levels. Qualitative properties of the model are formally established and simulations are shown as examples of its use. type 2 diabetes mellitus mathematical model glucose insulin beta-cell mass diabetes tipa 2 matematični modei glukoza inzulin true false true Elsevier Angleški jezik Slovenski jezik https://www.sciencedirect.com/journal/journal-of-theoretical-biology © 2024 The Authors Članek v reviji 2026-01-28 07:47:32 2026-01-28 07:47:33 2026-01-29 03:11:46 0000-00-00 00:00:00 2024 0 0 17 str. Vol. 587, [article no.] 111822 June 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2023-10-25 2024-03-27 2024-04-07 616.378 195458307 10.1016/j.jtbi.2024.111822 0022-5193 1-s2.0-S0022519324001036-main.pdf 1-s2.0-S0022519324001036-main.pdf 1 97B4E6F1B9774EDAAC0FBD459F8B60A0 1c71a56c23f1ca278936328695bc486ad0f11871badb6f5407df1e5cca01e415 bf150617-fc15-11f0-9a72-00155d00018d https://dk.um.si/Dokument.php?lang=slv&id=202657 https://www.sciencedirect.com/science/article/pii/S0022519324001036?via%3Dihub 0 c4c10c31-fc15-11f0-9a72-00155d00018d https://dk.um.si/Dokument.php?lang=slv&id=202658 Fakulteta za elektrotehniko, računalništvo in informatiko 0 0 0