20.500.12556/DKUM-96906 Vpliv kajenja elektronskih cigaret na razvoj kardiovaskularnih bolezni pri mladih odraslih Impact of e-cigarette smoking on the development of cardiovascular disease in young adults Uvod: Elektronske cigarete so v zadnjem desetletju postale razširjena oblika uporabe nikotina, posebej med mladimi odraslimi, kjer se pogosto dojemajo kot »varnejša« alternativa klasičnemu kajenju. Namen zaključnega dela je raziskati vpliv njihove uporabe na tveganje za razvoj kardiovaskularnih bolezni pri mladih odraslih. Metode: Izvedli smo pregled znanstvene literature. Literaturo smo iskali in pregledali v tujih podatkovnih bazah: PubMed, CINAHL Ultimate, Cochrane Library, Medline in Web of Science. Potek iskanja literature smo prikazali v PRISMA diagramu. Na koncu smo izvedli narativno sintezo zbranih raziskav. Rezultati: Skupno je bilo identificiranih 366 zadetkov, od tega je bilo v končno analizo vključenih 9 virov. Ugotovitve kažejo, da aerosoli elektronskih cigaret vsebujejo nikotin, težke kovine, aldehide in druge toksične snovi, ki so povezane z oksidativnim stresom, vnetjem in endotelijsko disfunkcijo. Opisani so akutni hemodinamski učinki: že enkratna uporaba lahko poveča srčni utrip za 3–4 utripe/min in sistolični krvni tlak za 2–3 mmHg; pri redni uporabi se učinki ponavljajo in lahko prispevajo k zgodnjim aterosklerotičnim spremembam. Poročano je tudi o povečani togosti arterij ter večjem tveganju za aritmije, hipertenzijo, možgansko kap in akutni miokardni infarkt. Razprava in zaključek: Čeprav se elektronske cigarete oglašujejo kot manj škodljiva alternativa klasičnim cigaretam, raziskave kažejo, da njihova uporaba prinaša številna tveganja za zdravje. Med mladimi odraslimi so e-cigarete vse bolj priljubljene zaradi privlačnih arom, vpliva družbenih omrežij in enostavne dostopnosti. Introduction: Electronic cigarettes have become a widespread form of nicotine use over the past decade, especially among young adults, where they are often perceived as a "safer" alternative to traditional smoking. The purpose of this thesis is to investigate the impact of their use on the risk of developing cardiovascular disease in young adults. Methods: We conducted a review of the scientific literature. We searched for and reviewed literature in foreign databases: PubMed, CINAHL Ultimate, Cochrane Library, Medline, and Web of Science. We presented the literature search process in a PRISMA diagram. Finally, we performed a narrative synthesis of the collected studies. Results: A total of 366 records were identified, of which 9 sources were included in the final analysis. The findings show that electronic cigarette aerosols contain nicotine, heavy metals, aldehydes, and other toxic substances associated with oxidative stress, inflammation, and endothelial dysfunction. Acute hemodynamic effects are described: even a single use can increase heart rate by 3–4 beats/min and systolic blood pressure by 2–3 mmHg; with regular use, the effects are repeated and may contribute to early atherosclerotic changes. Increased arterial stiffness and a higher risk of arrhythmias, hypertension, stroke, and acute myocardial infarction have also been reported. Discussion and conclusion: Although electronic cigarettes are advertised as a less harmful alternative to traditional cigarettes, research shows that their use poses numerous health risks. E-cigarettes are becoming increasingly popular among young adults due to their appealing flavors, the influence of social media, and their easy availability. kajenje elektronske cigarete nikotin bolezni srca in ožilja smoking electronic cigarettes nicotine cardiovascular disease true false false [N. Pušnik] Slovenski jezik Angleški jezik Diplomsko delo/naloga 2026-02-01 22:49:13 2026-04-15 16:56:29 2026-04-16 03:08:08 0000-00-00 00:00:00 2026 0 Maribor 0 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 613.84:615.22:616.1-053.6(043.2) 273724931 VS_Pusnik_Nina_2026.pdf VS_Pusnik_Nina_2026.pdf 1 EBFC6BDA03BD5FD0564A163DDF908EA1 9cf8c416287754fc54d546f3f17b24fc99e38ecd75fb9941a88a26f3aaa9d283 fa5e1211-09c6-11f1-895e-00155d00019a https://dk.um.si/Dokument.php?lang=slv&id=203359 Fakulteta za zdravstvene vede 0 0 0